GENERAL INFORMATION

DATAFILE: RawData_Pineda-Gomez_2025 // RawData_A new pharmacological strategy against treatment-resistant depression.txt
Excel table file containing raw data from Figures 2-5 and Table 1-2 divided in sheets, of the related paper.
	
ARTICLE:  A new pharmacological strategy against treatment-resistant depression.

JOURNAL:  Progress in Neuropsychopharmacology & Biological Psychiatry (2025)

AUTHORS:  Juan Pedro Pineda-Gómez, Carmelo Millón, Noelia Cantero-García, Marta Flores-Gómez, David Ladrón de Guevara-Miranda, Antonio Flores-Burgess*, Zaida Díaz-Cabiale.

Authors are from the Facultad de Medicina de Málaga, Facultad de Psicología de Málaga, Instituto de Investigación Biomédica de Málaga.

Emails:
juanpepineda@uma.es, afburgess@uma.es, carmelomp@uma.es, david.lgm@uma.es, noeliacg@uma.es, marta.fg28@uma.es, zaida@uma.es



METHODOLOGICAL INFORMATION

Figure 2: FST. Immobility time(s), swimming time(s); TST immobility time(s).
Figure 3: Components 1, 2 and 3 of PCA included the FST measures and the autoradiographic Kd parameters as variables (u.a.)
Figure 4: Components 1 and 2 of PCA included the FST measures and the autoradiographic Bmax parameters as variables (u.a.)
Figure 5: Corticosterone levels (ng/ml) 
Table 1: Autoradiographic ligand binding. Kd(nM), Bmax(fmol/mg prot)
Table 2: PCR. Normalized mRNA levels (u.a)

Groups were coded as:
FST - Forced swimming test
TST - Tail Suspension Test
PCR - Polymerase Chain Reaction
PCA - Principal Component Analysis.


Address questions to Antonio Flores-Burgess, e-mail: afburgess@uma.es