A revised electronic version of RUCAM for the diagnosis of DILI.

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LIPPINCOTT WILLIAMS & WILKINS

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Abstract

Roussel Uclaf Causality Assessment Method (RUCAM) for DILI has been hindered by subjectivity and poor reliability. We sought to improve the RUCAM using data from the Drug-Induced Liver Injury Network (DILIN) and the Spanish DILI Registry, published literature, and iterative computer modeling.

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Hayashi PH, Lucena MI, Fontana RJ, Bjornsson ES, Aithal GP, Barnhart H, Gonzalez-Jimenez A, Yang Q, Gu J, Andrade RJ, Hoofnagle JH. A revised electronic version of RUCAM for the diagnosis of DILI. Hepatology. 2022 Jul;76(1):18-31. doi: 10.1002/hep.32327. Epub 2022 Mar 22. PMID: 35014066; PMCID: PMC9233102.

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Except where otherwised noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional