In vitro viral coexistence decreases Striped Jack Nervous Necrosis Virus (SJNNV) but favours Red-spotted Grouper Nervous Necrosis Virus (RGNNV) replication

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European Association of Fish Pathologists

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In this study, several assays have been performed to characterise the effect of the RGNNV-SJNNV coexistence (coinfection and superinfection) on the replication of each genotype on E-11 cells.The results obtained showed the partial inhibition of the SJNNV replication in presence of RGNNV, whereas the RGNNV replication got favoured in either coinfection or superinfection with SJNNV. In addition, no competence for cellular receptors between these two genotypes has been observed.

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