RT Journal Article T1 An integrated biorefinery approach based on spent coffee grounds valorization A1 Pérez-Merchán, Antonio Manuel A1 Moreno-Tost, Ramón A1 Malpartida-García, Irene A1 García-Sancho, Cristina A1 Mérida-Robles, Josefa María A1 Maireles-Torres, Pedro Jesús K1 Café - Uso AB Spent coffee grounds (SCGs) are an abundant lignocellulosic biomass with significant potential for industrial valorization, with great social and environmental benefits, due to their rich composition in cellulose, hemicellulose and lignin. In this study, the organosolv process, a method widely used in the paper industry, was employed to efficiently fractionate SCGs into their primary components. Hemicellulosic liquors containing up to 25 wt% sugars, predominantly galactose and mannose, were successfully extracted and subsequently dehydrated to produce 5-hydroxymethylfurfural (5-HMF), reaching a maximum yield of 90 % within 15 min of reaction time. The residual cellulose and lignin fractions were characterized by X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR), confirming their effective separation. These findings highlight the viability of SCGs as a sustainable feedstock for biorefinery applications, contributing to waste valorization and the development of a circular economy. PB Elsevier YR 2025 FD 2025 LK https://hdl.handle.net/10630/40296 UL https://hdl.handle.net/10630/40296 LA eng NO Antonio M. Pérez-Merchán, Ramón Moreno-Tost, Irene Malpartida-García, Cristina García-Sancho, Josefa M. Mérida-Robles, Pedro Maireles-Torres, An integrated biorefinery approach based on spent coffee grounds valorization, Journal of Cleaner Production, Volume 528, 2025, 146716, ISSN 0959-6526, https://doi.org/10.1016/j.jclepro.2025.146716 DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 24 ene 2026