RT Journal Article T1 Impulsivity Is Related to Prescription Opioid Misuse in People With Chronic Pain Through Pain Catastrophizing and Emotional Distress. A1 Esteve-Zarazaga, Rosa A1 Ramírez-Maestre, María del Carmen A1 Serrano-Ibáñez, Elena Rocío A1 López-Martínez, Alicia Eva K1 Ansiedad K1 Depresión mental K1 Opiáceos - Abuso AB AbstractBackground: This study investigated the role of impulsivity as a personality variable predisposing to prescription opioid misuse. Pain catastrophizing, as well as anxiety, depression, and pain intensity, were postulated as potential serial mediators in this relationship.Methods: The sample comprised 366 individuals with chronic pain. We conducted correlational and serial mediation analyses to investigate the relationships between the study variables.Results: The results showed that pain catastrophizing partially mediated the relationship between impulsivity and prescription opioid misuse. Depression and anxiety also partially mediated the relationship between pain catastrophizing and prescription opioid misuse, although pain intensity did not mediate this relationship. Impulsivity was also indirectly associated with prescription opioid misuse through pain catastrophizing, anxiety, and depression.Conclusions: Our findings highlight the key role of impulsivity in prescription opioid misuse and contribute to understanding its mechanisms of action. Based on these results, clinical interventions could target emotion-related impulsivity and cognitive control deficits to reduce rumination. Future research could investigate the relationships identified in this study using the specific dimensions of impulsivity. PB Wiley YR 2025 FD 2025-09-24 LK https://hdl.handle.net/10630/40145 UL https://hdl.handle.net/10630/40145 LA eng NO Esteve, R., Ramírez-Maestre, C., Serrano-Ibáñez, E. R., & López-Martínez, A. E. (2025). Impulsivity Is Related to Prescription Opioid Misuse in People With Chronic Pain Through Pain Catastrophizing and Emotional Distress. Pain Research and Management, 2025(1), 6315721. NO Ministerio de Ciencia e Innovación (España) NO Junta de Anadalucía NO Fondos FEDER NO D2019-106086RB- I00 NO HUM-566 NO UMA20-FEDERJA-118 DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 19 ene 2026