RT Journal Article
T1 Fundamental limit of detection of photonic biosensors with coherent phase read-out
A1 Molina-Fernández, Íñigo
A1 Leuermann, Jonas
A1 Ortega-Moñux, Alejandro
A1 Wanguemert-Pérez, Juan Gonzalo
A1 Halir, Robert
K1 Detectores
AB Photonic biosensors offer label-free detection of biomolecules for applicationsrangingfromclinicaldiagnosistofoodqualitymonitoring. BothsensorsbasedonMach-Zehnderinterferometers and ring resonators are widely used, but are usually read-out using differentschemes, making a direct comparison of their fundamental limit of detection challenging. Acoherent detection scheme, adapted from optical communication systems, has been recentlyshowntoachieveexcellentdetectionlimits,usingasimplefixed-wavelengthsource. Herewepresent, for the first time, a theoretical model to determine the fundamental limit of detection ofsuchacoherentread-outsystem,forbothinterferometricandresonantsensors. Basedonthisanalysis,weprovideguidelinesforsensoroptimizationinthepresenceofopticallossesandshowthatinterferometricsensorsarepreferableoverresonantstructureswhenthesensorsizeisnotlimited bythe available samplevolume.
PB Optica Publishing Group
YR 2019
FD 2019-04-01
LK https://hdl.handle.net/10630/36023
UL https://hdl.handle.net/10630/36023
LA eng
NO Íñigo Molina-Fernández, Jonas Leuermann, Alejandro Ortega-Moñux, J. Gonzalo Wangüemert-Pérez, and Robert Halir, "Fundamental limit of detection of photonic biosensors with coherent phase read-out," Opt. Express 27, 12616-12629 (2019)
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026