RT Journal Article
T1 Use of ultra-wide field retinal imaging and optical coherence tomography angiography in the diagnosis of incomplete Susac syndrome.
A1 Alba-Linero, Carmen
A1 Liscombe-Sepulveda, John Paul
A1 Llorenç, Víctor
A1 GiraltJosa, Joan
A1 Adán, Alfredo
K1 Ojos - Inflamación
K1 Uveítis
K1 Inmunología
K1 Sistema cardiovascular - Enfermedades
AB El artículo se centra en el diagnóstico de la Síndrome de Susac (Susac syndrome) incompleto mediante técnicas avanzadas de imagen: imágenes de campo ultra amplio (ultra wide field, UWF) de la retina y angio tomografía de coherencia óptica (OCT A).
AB Purpose:To describe clinical findings through ultra-wide field (UWF) images and optical coherence tomography angiography (OCT-A), in Susac’s syndrome (SS).Methods:SS patients were retrospectively analyzed in a single center. Clinical features, ultra-wide-field retinographies (UWF-PR), UWF fluorescein angiographies (UWF-FA), and optical coherence tomography angiography & en face (OCT-A/EF) were reviewed.Results:Twelve eyes from six patients with a mean follow-up of 35.66 months ± SD 36.88 were included. UWF-PR showed areas of retinal whitening and cotton-wool spots in all the eyes after acute attack. Segmentary mid peripheral arteriolitis could be observed in five eyes by UWF-FA in acute and convalescent stages. OCT-A revealed capillary density changes in all of the affected eyes. During the acute phase there was a well-preserved superficial capillary network, while deep retinal plexus showed a lower density in the affected areas. OCT-A/EF revealed deep retinal plexus drop-out and surrounding edematous retina in acute attacks, becoming atrophic over time. Conversely, superficial plexus was much less affected. Perifoveal reperfusion was seen in seven eyes after the acute attack.Conclusions:UWF-PR/FA and OCT-A/EF might be helpful to stablish an early diagnosis and to monitor SS progression.
PB Sage
YR 2020
FD 2020-10-26
LK https://hdl.handle.net/10630/40978
UL https://hdl.handle.net/10630/40978
LA eng
NO Alba-Linero C, Liscombe-Sepúlveda JP, Llorenç V, GiraltJosa J, Adán A. Use of ultra-wide field retinal imaging and optical coherence tomography angiography in the diagnosis of incomplete Susac syndrome. Eur J Ophthalmol. 2021 Nov;31(6):3238-3247. doi: 10.1177/1120672120965482. Epub 2020 Oct 26. PMID: 33106042.
NO https://openpolicyfinder.jisc.ac.uk/id/publication/11477
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 22 ene 2026