RT Conference Proceedings
T1 Synthesis and antibacterial activity of bimetallic carboxyphosphonates
A1 Cabeza-Díaz, Aurelio
A1 Pérez-Colodrero, Rosario Mercedes
A1 Vílchez-Cózar, Álvaro
A1 Olivera-Pastor, Pascual
A1 Hix, Gary B.
A1 Bazaga-García, Montse
K1 Química inorgánica
K1 Polímeros
AB As a class of coordination polymers (CPs), metal phosphonates (MPs) are constructed by coordination bonds connecting metal sites and phosphonate (RPO3 2−) ligands, where the metal sites are dispersed uniformly at the atomic level. The synthetic chemistry of phosphonates is well developed, so phosphonic acids can be obtained through simple, well-known reactions, enabling the synthesis of phosphonate derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) to be carried out. We report here, general characteristics of a new series of isostructural compounds resulting from the combination of the multifunctional R,S-hydroxyphophonoacetic acid (HPAA) with transition metal ions, AgMII[HO3PCH(OH)COO] (MII= Co or Zn), AgMHPAA. Both compounds were synthesized under hydrothermal conditions and their crystal structures were solved from single crystal diffraction data.The antibacterial activity of AgZnHPAA and AgCoHPAA was evaluated using three different bacterial strains: Staphylococcus aureus (NCIMB 6571), Escherichia coli K12 W-T (W1485 Cardiff Collection) and Pseudomonas aeruginosa (NCIMB 8295). Preliminary results regarding their antibacterial properties will be presented and discussed.
YR 2023
FD 2023
LK https://hdl.handle.net/10630/25797
UL https://hdl.handle.net/10630/25797
LA eng
NO Universidad de Málaga. Campus de Excelencia Interna Andalucía Tech.Proyectos nacionales MAT2016-77648-R y PID2019-110249RB-I00cional
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 ene 2026