RT Journal Article
T1 Land- and water-based aerobic exercise program on health-related outcomes in breast cancer survivors (WaterMama): study protocol for a randomized clinical trial
A1 Lima Alberton, Cristine
A1 Siqueira Andrade, Luana
A1 Botelho Xavier, Bruno Ezequiel
A1 Guesser Pinheiro, Victor Hugo
A1 Cuesta-Vargas, Antonio
A1 Santana Pinto, Stephanie
K1 Ejercicio físico - Uso terapéutico
AB Background: Breast cancer is a prevalent form of cancer among women worldwide, often accompanied by physical and psychological side effects due to the disease and the treatment's aggressiveness. Regular physical exercise has emerged as a non-pharmacological approach to improve the quality of life of breast cancer survivors. We herein report the protocol of the WaterMama Study, which aims to evaluate the effects of land- or water-based aerobic exercise programs, compared to a health education program, on cancer-related fatigue and other health-related outcomes in breast cancer survivors.Methods: The WaterMama trial is a randomized, single-blinded, three-arm, parallel, superiority trial. We aim to recruit 48 women ≥ 18 years of age who have completed primary treatment for stage I-III breast cancer. Participants are randomly allocated in a 1:1:1 ratio to 12-week interventions of aerobic exercise training programs either in the aquatic or land environment (two weekly 45-min sessions) plus health education (a weekly 45-min session), or an active-control group receiving health education alone (a weekly 45-min session). The primary outcome is cancer-related fatigue, and the secondary outcomes include cardiorespiratory fitness, muscular performance, muscle morphology, functional capacity, mental health, cognitive function, pain, and quality of life. Outcomes assessments are conducted before and after the 12-week intervention period. The analysis plan will employ an intention-to-treat approach and per protocol criteria.Discussion: Our conceptual hypothesis is that both aerobic exercise programs will positively impact primary and secondary outcomes compared to the health education group alone. Additionally, due to its multi-component nature, we expect the aquatic exercise program promote more significant effects than the land exercise program on cancer-related fatigue, muscular outcomes, and pain.
PB BMC Springer Nature
YR 2024
FD 2024-08-13
LK https://hdl.handle.net/10630/35722
UL https://hdl.handle.net/10630/35722
LA eng
NO Alberton, C.L., Andrade, L.S., Xavier, B.E.B. et al. Land- and water-based aerobic exercise program on health-related outcomes in breast cancer survivors (WaterMama): study protocol for a randomized clinical trial. Trials 25, 536 (2024). https://doi.org/10.1186/s13063-024-08389-y
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 ene 2026