RT Conference Proceedings
T1 Translational regulation of hormone synthesis and signaling mRNAs
A1 Duarte-Conde, José Antonio
A1 Sans-Coll, Gemma
A1 Fernández-Pozo, Noé
A1 Pulido Navarro, Aurora
A1 Merchante-Berg, Catharina
K1 Hormonas vegetales
K1 Regulación celular vegetal
AB Translational regulation has long been recognized as a vital process in the cell responses to the environment and in the execution of developmental programs, yet still little is known about the selective translation of specific mRNAs and its regulation (1).Our research tries to understand the role of translational regulation in developmental and environmental responses and to that, we are using different perspectives: 1) we are studying ribosome heterogeneity in Arabidopsis and trying to determine whether it is involved in the selective translation of specific mRNAs under different cell conditions, and 2) we are trying to identify the translational machinery and RNA-binding proteins involved in the translational regulation of hormonal pathways using well-known translationally regulated hormone- biogenesis and signaling genes (2-4). We have been able to show that certain ribosomal protein paralogs are required for the specific translation of uORF-containing hormone-related mRNAs, and are now trying to understand the molecular mechanisms that control this regulation. Our progress regarding this objective will be presented.
YR 2023
FD 2023
LK https://hdl.handle.net/10630/26385
UL https://hdl.handle.net/10630/26385
LA spa
NO This work has been funded by grants BIO2017-82720-P, RYC2017-22323, UMA20-FEDERJA-100, and PID2021-123240NB-100 to CM; a PRE2018-083348 fellowhip to JADC; and Plan Propio (UMA): Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 4 mar 2026