RT Journal Article T1 Sentiment Analysis on Twitter: Role of Healthcare Professionals in the Global Conversation during the AstraZeneca Vaccine Suspension A1 Ruiz-Núñez, Carlos A1 Herrera-Peco, Iván A1 Campos-Soler, Silvia María A1 Carmona-Pestaña, Álvaro A1 Benítez de Gracia, Elvira A1 Peña Deudero, Juan José A1 García-Notario, Andrés Ignacio K1 Medios sociales AB The vaccines against COVID-19 arrived in Spain at the end of 2020 along with vaccination campaigns which were not free of controversy. The debate was fueled by the adverse effects following the administration of the AstraZeneca-Oxford (AZ) vaccine in some European countries, eventually leading to its temporary suspension as a precautionary measure. In the present study, we analyze the healthcare professionals’ conversations, sentiment, polarity, and intensity on social media during two periods in 2021: the one closest to the suspension of the AZ vaccine and the same time frame 30 days later. We also analyzed whether there were differences between Spain and the rest of the world. Results: The negative sentiment ratio was higher (U = 87; p = 0.048) in Spain in March (Med = 0.396), as well as the daily intensity (U = 86; p = 0.044; Med = 0.440). The opposite happened with polarity (U = 86; p = 0.044), which was higher in the rest of the world (Med = −0.264). Conclusions: There was a general increase in messages and interactions between March and April. In Spain, there was a higher incidence of negative messages and intensity compared to the rest of the world during the March period that disappeared in April. Finally, it was found that the dissemination of messages linked to negative emotions towards vaccines against COVID-19 from healthcare professionals contributed to a negative approach to primary prevention campaigns in the middle of the pandemic PB IOAP-MDPI YR 2023 FD 2023-01-26 LK https://hdl.handle.net/10630/26070 UL https://hdl.handle.net/10630/26070 LA eng NO Ruiz-Núñez C, Herrera-Peco I, Campos-Soler SM, Carmona-Pestaña Á, Benítez de Gracia E, Peña Deudero JJ, García-Notario AI. Sentiment Analysis on Twitter: Role of Healthcare Professionals in the Global Conversation during the AstraZeneca Vaccine Suspension. International Journal of Environmental Research and Public Health. 2023; 20(3):2225. https://doi.org/10.3390/ijerph20032225 NO This research was funded by Fundación Banco Santander and Fundación Alfonso X el Sabio, grant number 1012031. Partial funding for open access charge: Universidad de Málaga DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026