RT Journal Article T1 Patient-reported impact of symptoms in schizophrenia scale (PRISS): Development and validation A1 Moreno-Kustner, Berta A1 Fábrega-Ruz, Julia A1 Gonzalez-Caballero, A1 Reyes-Martin, Sara A1 Ochoa, Susana A1 Romero-Lopez-Alberca, Cristina A1 Cid, Jordi A1 Vila-Badia, Regina A1 Frigola-Capell, Eva A1 Salvador-Carulla, Luis K1 Esquizofrenia AB BackgroundWe report the psychometric properties of the Patient-Reported Impact of Symptoms in Schizophrenia Scale (PRISS), which assesses the impact of subjective experiences or qualia in outpatients with this condition.MethodsA cross-sectional study was carried out in 162 patients diagnosed with schizophrenia in Spain. The PRISS measures the presence, frequency, concern and interference with daily life of self-reported experiences related to the main symptoms observed in these patients. The psychometric analysis included test-retest reliability, internal consistency and structural and convergent validity.ResultsThe 28-item PRISS showed good test-retest reliability as 64.3% of the intraclass correlation coefficient values were between 0.40 and 0.79, which were statistically significant (p < 0.01). Analysis of the structural validity revealed a three-factor structure, (1) productive subjective experiences, (2) affective-negative subjective experiences and (3) excitation, which accounted for 56.11% of the variance. Of the Pearson's correlation coefficients analysed between the PRISS and the Positive and Negative Syndrome Scale (PANSS), Scale for Assessment of Negative Symptoms (SANS) and World Health Organization Disability Assessment Schedule (WHO-DAS), 72.2% were statistically significant (p < 0.05) and ranged from 0.38–0.42, 0.32–0.42 and 0.40–0.42, respectively.ConclusionOur results indicate that the PRISS appears to be a brief, reliable and valid scale to measure subjective experiences in schizophrenia and provides valuable information complementary to clinical evaluation. PB Wiley YR 2022 FD 2022-02-21 LK https://hdl.handle.net/10630/25773 UL https://hdl.handle.net/10630/25773 LA eng NO Moreno-Küstner, B, Fábrega-Ruz, J, Gonzalez-Caballero, JL, et al. Patient-reported impact of symptoms in schizophrenia scale (PRISS): Development and validation. Acta Psychiatr Scand. 2022; 145: 640– 655. doi:10.1111/acps.13417 NO This study has been funded by the ‘Instituto de Salud Carlos III’ through the project PI16/00647 and co- funded by the European Regional Development Fund (FEDER) ‘A way to make Europe’. Funding for open access charge: Universidad de Málaga / CBUA DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 4 mar 2026