RT Conference Proceedings
T1 A model of maxilla resection to test new hybrid implants:macroporous titanium and tissue engineering elements
A1 Santos-Ruiz, Leonor
A1 Monopoli, Donato
A1 Yáñez Vilas, José Ignacio
A1 Mentado, Belinda
A1 Ruiz, F
A1 Argárate, N
A1 Granados, F
A1 Arrabal-García, Pilar María
A1 Belmonte, Rosa María
A1 Becerra-Ratia, José
K1 Implantes dentales
AB Maxillary bone loss in commonly found in humans, due to bone ageing, tooth loos, periodontal disease and, more severely, to trauma, radiotherapy and tumor resection. Masillofacial reconstructive surgery is a still unmet clinical demand, available therapies include grafting of autologous or heterologous bone tissue and/or the implantation of metallic plates, buy these treatments are still unable to resume form and function. The emrgence of 3D-printing technology applied to metal alloys now allows the manufacturing of customized, patient-tailored prosthetic implants. However, poor bone quiality at the implant site due to ageing or disease still hamper proper osseointegration. By combining Electron Beam Melting metal sintering and tissue engineering, we are developing hybrid maxillofacial implants, wher a metal framework of Ti6Al4V alloy confers both and appropiaate shape and mechanical stabilty, while stem cells and osteogenic  molecules stimulate bone growth into the metal framework, thus pormoting osseointegration. We hereby present the in vitro work driving to the development of our hybrid  maxillofacial prostheses, as well as the setting up of an in vivo model of complete maxilla full resection, created in order to test the prostheses in a preclinical study
YR 2015
FD 2015-07-23
LK http://hdl.handle.net/10630/10138
UL http://hdl.handle.net/10630/10138
LA eng
NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026