RT Journal Article
T1 Infant neurocognitive development is independent of the use of iodised salt or iodine supplements given during pregnancy
A1 Santiago, Piedad
A1 Velasco, Inés
A1 Muela-Zarzuela, Inés
A1 Sánchez, Baltasar
A1 Martínez, Julia
A1 Rodríguez, Álvaro
A1 Berrio, María
A1 Gutiérrez-Repiso, Carolina
A1 Carreira-Soler, Mónica
A1 Moreno, Alberto
A1 García-Fuentes, Eduardo
A1 Soriguer, Federico
K1 Embarazo - Complicaciones y secuelas
AB The benefits of iodine supplements during pregnancy remain controversial in areas with a mild-to-moderate iodine deficiency. The aim of the present study was to determine the effect of improving iodine intakes, with iodised salt (IS) or iodine supplements, in pregnant Spanish women. A total of 131 pregnant women in their first trimester were randomly assigned to three groups: (1) IS in cooking and at the table, (2) 200 μg potassium iodide (KI)/d or (3) 300 μg KI/d. No differences were found in thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3) or thyroid volume (TV) between the three groups. Regardless of the group in which women were included, those who had been taking IS for at least 1 year before becoming pregnant had a significantly lower TV in the third trimester (P= 0·01) and a significantly higher urinary iodine in the first (173·7 (sd 81·8) v. 113·8 (sd 79·6) μg/l, P= 0·001) and third trimesters (206·3 (sd 91·2) v. 160·4 (sd 87·7) μg/l, P= 0·03). Also, no differences were seen in TSH, FT4 or FT3. Children's neurological development was not significantly associated with the consumption of IS for at least 1 year before becoming pregnant and no differences were found according to the treatment group. In conclusion, in pregnant women with insufficient iodine intake, the intake of IS before becoming pregnant was associated with a better maternal thyroid function. The form of iodide intake was not associated with maternal thyroid function or children's neurological development.
PB Cambridge University Press
YR 2013
FD 2013
LK https://hdl.handle.net/10630/37240
UL https://hdl.handle.net/10630/37240
LA eng
NO P Santiago; I Velasco; JA Muela; B Baltasar Sánchez; J Martinez; A Rodriguez; M Berrio; C Gutierrez-Repiso; M Carreira; A Moreno; E Garcia-Fuentes; F Soriguer. Infant neurocognitive development is independent on the use of iodized salt or iodine supplements given during pregnancy. British Journal of Nutrition. 110, pp. 831 - 839. 2013. doi: 10.1017/S0007114512005880.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 ene 2026