RT Journal Article
T1 ptm: an R package for the study of methionine sulfoxidation and other posttranslational modifications.
A1 Aledo-Ramos, Juan Carlos
K1 Bioinformática
K1 Metionina
K1 Modificación postraslacional
AB Summary: Methionine sulfoxidation is a posttranslational modification (PTM) playing important roles in cell signal-ing. Herein, we present ptm, an R package for the study of this modification. However, since many of the analysesapplied to methionine modification can be extended to other modifications, the package can be useful to thoroughlyanalyze PTMs in general. Thus, within a single software environment, ptm can integrate information from up to 11databases covering nine modifications. Different functions can work coordinately to form pipelines allowing the pro-grammatic analysis of thousands of proteins. Alternatively, the user can simultaneously perform different analyseson the same protein of interest, combining the results into a single output. The flexibility of ptm makes it a suitabletool to address site- and protein-centric hypotheses related to PTMs. Accompanying the package, we maintain aweb page containing extended documentation and examples of the tasks that can be performed with ptm.Availability and implementation: ptm is implemented in R. Release versions are available via CRAN and work on allmajor operating systems. The development version is maintained at https://bitbucket.org/jcaledo/ptm. Extendeddocumentation can be found at https://metositeptm.com
PB Oxford
YR 2021
FD 2021-05-08
LK https://hdl.handle.net/10630/40158
UL https://hdl.handle.net/10630/40158
LA eng
NO Juan Carlos Aledo, ptm: an R package for the study of methionine sulfoxidation and other posttranslational modifications, Bioinformatics, Volume 37, Issue 21, November 2021, Pages 3979–3980, https://doi.org/10.1093/bioinformatics/btab348
NO UMA18-FEDERJA-149.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 28 ene 2026