RT Journal Article
T1 The Mediating Role of Psychological Flexibility and Inflexibility Between Impulsivity and Opioid Misuse in People With Chronic Noncancer Pain
A1 Barrado-Moreno, Victoria
A1 Esteve-Zarazaga, Rosa
A1 McCracken, Lance M.
A1 Ramírez-Maestre, María del Carmen
K1 Opiáceos - Abuso
K1 Dolor - Aspectos psicológicos
K1 Adaptación (Psicología)
AB BackgroundThe prescription of opioid medication is a frequent therapeutic approach in chronic noncancer pain, as is misuse of prescribed opioids. There is previous evidence for associations between personal variables such as impulsivity and opioid misuse. Psychological flexibility and inflexibility have also been associated with pain-related outcomes and opioid misuse. The aim of this cross-sectional study was to examine the combined role of a dispositional variable (impulsivity) along with psychological factors (Psychological Flexibility and Inflexibility) in pain outcomes and opioid misuse.MethodsThe sample comprised 155 people with chronic noncancer pain. A hypothetical model was tested using correlation and structural equation modelling analyses.ResultsThe results show significant associations between impulsivity and Psychological Flexibility, Psychological Inflexibility and opioid misuse. Psychological Flexibility and Inflexibility were related to pain intensity, interference and opioid misuse. Structural equation modelling showed significant associations between impulsivity, Psychological Inflexibility and pain interference, and opioid misuse. Associations between Psychological Flexibility and pain interference and opioid misuse were nonsignificant. These results support the hypothesis that impulsivity and Psychological Inflexibility are factors that contribute to pain interference and opioid misuse, but do not support the hypothesis that Psychological Flexibility reduces opioid misuse.ConclusionsIt is recommended to assess these psychological aspects prior to the prescription of opioid medication, and, if necessary, offering Acceptance and Commitment and Mindfulness Based Therapies could be desirable.
PB Wiley
SN 1090-3801
YR 2025
FD 2025-05-26
LK https://hdl.handle.net/10630/39082
UL https://hdl.handle.net/10630/39082
LA eng
NO Barrado‐Moreno, V., Esteve, R., McCracken, L. M., & Ramírez‐Maestre, C. (2025). The Mediating Role of Psychological Flexibility and Inflexibility Between Impulsivity and Opioid Misuse in People With Chronic Noncancer Pain. European Journal of Pain, 29(6).
NO Funding for open access charge: Universidad de Málaga / CBUA
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 4 mar 2026