RT Generic T1 Dataset for: A persistent increase in gut permeability correlates with emotional dysregulation following maternal separation in male and female mice. A1 Castro-Zavala, Adriana A1 Nieto-Nieves, Ana A1 Melgar-Locatelli, Sonia A1 Medina-Rodríguez, Lidia A1 Mañas-Padilla, María del Carmen A1 Castilla-Ortega, María Estela K1 Estrés (Fisiología) K1 Mediadores de la inflamación K1 Sistema nervioso - Inflamación K1 Intestinos - Permeabilidad K1 Ansiedad K1 Depresión mental K1 Diferencias sexuales AB Early life stress (ELS) can significantly influence vulnerability to the development ofpsychiatric disorders in adulthood. One of the most widely used preclinical models forinvestigating ELS is maternal separation with early weaning (MSEW), which mimicsearly-life neglect. The objective of this study was to evaluate the impact of ELS inducedby MSEW on the emotional behaviour of male and female mice, as well as its relationshipwith intestinal permeability and neuroinflammatory markers in the hippocampus. PB Universidad de Málaga YR 2025 FD 2025-04-03 LK https://hdl.handle.net/10630/38396 UL https://hdl.handle.net/10630/38396 LA eng DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 24 ene 2026