RT Journal Article
T1 Sex-Specific Relationships of Physical Activity and Sedentary Behaviour with Oxidative Stress and Inflammatory Markers in Young Adults
A1 Corral Pérez, Juan
A1 Alcala, Martin
A1 Velázquez-Díaz, Daniel
A1 Pérez-Bey, Alejandro
A1 Vázquez-Sánchez, María Ángeles
A1 Calderón Domínguez, María
A1 Casals, Cristina
A1 Ponce González, Jesús Gustavo
K1 Ejercicio físico
AB This study aims to analyse sex-specific associations of physical activity and sedentary behaviour with oxidative stress and inflammatory markers in a young-adult population. Sixty participants (21 women, 22.63 ± 4.62 years old) wore a hip accelerometer for 7 consecutive days to estimate their physical activity and sedentarism. Oxidative stress (catalase, superoxide dismutase, glutathione peroxidase, glutathione, malondialdehyde, and advanced oxidation protein products) and inflammatory (tumour necrosis factor-alpha and interleukin-6) markers were measured. Student t-tests and single linear regressions were applied. The women presented higher catalase activity and glutathione concentrations, and lower levels of advanced protein-oxidation products, tumour necrosis factor-alpha, and interleukin-6 than the men (p < 0.05). In the men, longer sedentary time was associated with lower catalase activity (β = −0.315, p = 0.04), and longer sedentary breaks and higher physical-activity expenditures were associated with malondialdehyde (β = −0.308, p = 0.04). Vigorous physical activity was related to inflammatory markers in the women (tumour necrosis factor-alpha, β = 0.437, p = 0.02) and men (interleukin−6, β = 0.528, p < 0.01). In conclusion, the women presented a better redox and inflammatory status than the men; however, oxidative-stress markers were associated with physical activity and sedentary behaviours only in the men. In light of this, women could have better protection against the deleterious effect of sedentarism but a worse adaptation to daily physical activity.
PB IOAP-MDPI
YR 2023
FD 2023-01-04
LK https://hdl.handle.net/10630/25993
UL https://hdl.handle.net/10630/25993
LA eng
NO Corral-Pérez J, Alcala M, Velázquez-Díaz D, Perez-Bey A, Vázquez-Sánchez MÁ, Calderon-Dominguez M, Casals C, Ponce-González JG. Sex-Specific Relationships of Physical Activity and Sedentary Behaviour with Oxidative Stress and Inflammatory Markers in Young Adults. International Journal of Environmental Research and Public Health. 2023; 20(2):899. https://doi.org/10.3390/ijerph20020899
NO This work was partly supported by Universidad de Cádiz (grant number PR2016-051 and PR2019-054), by Instituto de Investigación e Innovación Biomédica de Cádiz (LI19/21IN-CO09), and by the Spanish Ministry of Science and Innovation (Ministerio de Ciencia e Innovación) (MCIN/AEI/ 10.13039/501100011033), grants PID2019-110063RA-I00 and PID2020-120034RA-I00. J.C.-P. is supported by a predoctoral grant from the Spanish Ministry of Education (Ministerio de Educación) (grant number FPU19/02326). D.V.-D is funded by the Margarita Salas Postdoctoral Program from European Union Next GenerationEU and University of Cádiz. Partial funding for open access charge: Universidad de Málaga
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 4 mar 2026