RT Journal Article T1 Vulnerability Factors, Adjustment, and Opioid Misuse in Chronic Non-Cancer Pain Individuals. A1 Ramírez-Maestre, María del Carmen A1 Barrado-Moreno, Victoria A1 Esteve-Zarazaga, Rosa A1 Serrano-Ibáñez, Elena Rocío A1 De la Vega, Rocío A1 Ruiz-Párraga, Gema Teresa A1 Fernández Baena, Mariano A1 Jensen, Mark P. A1 López-Martínez, Alicia Eva K1 Dolor crónico K1 Opiáceos - Uso terapéutico K1 Medicamentos - Abuso K1 Dolor - Aspectos psicológicos AB There are several person variables that pre-date injury or pain onset that increase the probability of maladjustment to pain and opioid misuse. The aim of this study was to evaluate the role of two diathesis variables (impulsiveness and anxiety sensitivity) in the adjustment of individuals with chronic noncancer pain and in the opioid misuse. The sample comprised 187 individuals with chronic noncancer pain. The hypothetical model was tested using correlation and structural equation modelling analyses. The results show a significant association between impulsiveness and anxiety sensitivity and all the maladjustment variables, and between impulsiveness and anxiety sensitivity and opioid misuse and craving. However, although the correlation analysis showed a significant association between adjustment to pain and opioid misuse, the SEM analysis showed a nonsignificant association between them (as latent variables). The findings support the hypothesis that both impulsiveness and anxiety sensitivity are vulnerability factors for maladaptive adjustment to chronic pain and opioid misuse. PB Elsevier YR 2024 FD 2024 LK https://hdl.handle.net/10630/31864 UL https://hdl.handle.net/10630/31864 LA spa NO Ramírez-Maestre, C.; Barrado-Moreno, V.; Esteve, R.; Serrano-Ibáñez, ER; de la Vega, R.; Ruíz-Párraga, GT.; Fernández Baena, M.; Jensen, M. & López-Martínez, AE. (2024). Vulnerability Factors, Adjustment, and Opioid Misuse in Chronic Non-Cancer Pain Individuals, Journal of Pain, https://doi.org/10.1016/j.jpain.2024.104606 NO This research was supported by grants from the Spanish Ministry of Science and Innovation (PID2019-106086RB-I00) and the Andalusian Regional Government (HUM-566; UMA20-FEDERJA-118). VB’s work is supported by the Spanish Ministry of Science and Innovation with the contract PRE2020-093204. RV’s work is supported by the Spanish Ministry of Science and Innovation with a Ramon y Cajal contract (RYC2018-024722-I). GST’s work is supported by the Andalusian Regional Government with the contract PREDOC-00023.Funding for open access charge: Universidad de Málaga / CBUA DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 4 mar 2026