RT Journal Article T1 Efect of a 12-week exercise program on phase angle in women with breast cancer. A1 Escriche-Escuder, Adrián A1 García-Almeida, José Manuel A1 Vegas-Aguilar, Isabel María A1 Pajares, Bella A1 Alba-Conejo, Emilio A1 Trinidad-Fernández, Manuel A1 Roldán-Jiménez, Cristina A1 Cuesta-Vargas, Antonio K1 Mamas - Cáncer K1 Cáncer - Fisioterapia K1 Cáncer - Ejercicios terapéuticos AB PurposeThe aims of this study were to analyze the effects of a 12-week exercise intervention on bioelectrical impedance analysis-derived phase angle (PhA), resistance (R), and reactance (Xc) in breast cancer survivors (BCS) and analyze the relationship between changes in bioelectrical impedance variables and changes in functional capacity and muscular strength.MethodsThis was a prospective cohort study. Potentially eligible patients were recruited from the Medical Oncology Unit of the hospital. Female BCS older than 18 years were offered to participate in the study if they had previously undergone surgery for their primary tumor and there was no evidence of recurrence at the time of recruitment. A 12-week exercise program including resistance and endurance training was performed, including two weekly sessions led by a physical therapist. Measurements were performed at baseline and after 12 weeks, including PhA and function-related outcomes. The relationship between changes in PhA and function-related outcomes was assessed using the Pearson r correlation coefficient.ResultsSixty-seven BCS women were included in the analysis. A significant increase was found in PhA and functional outcomes after the intervention, as well as a significant decrease in R. Bivariate correlations showed a significant positive correlation between PhA and functional tests (Hand grip, r = 0.37 [p = 0.002], 30-Sit to Stand, r = 0.39 [0.002], respectively).ConclusionA 12-week concurrent exercise program may be effective to improve PhA and R. Additionally, there appears to be a correlation between PhA and Xc with functional capacity outcomes. Finally, baseline PhA, Xc, and R values explained part of the 30-STS and hand grip tests variance at 12 weeks, which could suggest its importance in the prognosis. PB Springer Nature SN 0941-4355 YR 2025 FD 2025-04-21 LK https://hdl.handle.net/10630/38470 UL https://hdl.handle.net/10630/38470 LA eng NO Escriche-Escuder, A., García-Almeida, J.M., Vegas-Aguilar, I.M. et al. Effect of a 12-week exercise program on phase angle in women with breast cancer. Support Care Cancer 33, 398 (2025). NO Funding for open access charge: Universidad de Málaga / CBUA DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 12 abr 2026