RT Journal Article
T1 Standardizing single-cell approaches to osteoarthritis: Toward a comprehensive cellular atlas
A1 Delgado-Sánchez, Iván
A1 Fernández-Pozo, Noé
A1 Durán-Jimenez, Iván Jesús
K1 Artrosis
K1 Citología
K1 Acido ribonucleico
AB Osteoarthritis (OA) is a degenerative joint disease marked by progressive cartilage degradation and complexcellular heterogeneity. In recent years, single-cell RNA sequencing (scRNA-seq) has emerged as a powerfultool for dissecting the cellular composition of the osteoarthritic joint. However, constructing a complete andcoherent picture of the OA single-cell landscape remains challenging, akin to assembling a puzzle frommultiple sets, each with pieces of varying shapes and sizes. This editorial outlines the next steps in advancing single-cell research in OA, emphasizing the need for standardized cell type annotations andcomprehensive, integrative access to both historical and newly generated datasets.
PB Elsevier
YR 2025
FD 2025
LK https://hdl.handle.net/10630/40526
UL https://hdl.handle.net/10630/40526
LA eng
NO Delgado-Sanchez, I., Fernandez-Pozo, N., & Duran, I. (2025). Standardizing single-cell approaches to osteoarthritis: Toward a comprehensive cellular atlas. Osteoarthritis and Cartilage. Advance online publication. https://doi.org/10.1016/j.joca.2025.08.016
NO Funding for open access charge: Universidad de Málaga/CBUA
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026