RT Journal Article
T1 The Crucial Role of Inflammation and the Immune System in Colorectal Cancer Carcinogenesis: A Comprehensive Perspective.
A1 Burgos-Molina, Antonio Manuel
A1 Téllez-Santana, Teresa
A1 Redondo-Bautista, Maximino
A1 Bravo-Romero, María José
K1 Colon (Anatomía) - Cáncer
K1 Inflamación (Patología)
AB Chronic inflammation drives the growth of colorectal cancer through the dysregulation of molecular pathways within the immune system. Infiltration of immune cells, such as macrophages, into tumoral regions results in the release of proinflammatory cytokines (IL-6; IL-17; TNF-α), fostering tumor proliferation, survival, and invasion. Tumors employ various mechanisms to evade immune surveillance, effectively ‘cloaking’ themselves from detection and subsequent attack. A comprehensive understanding of these intricate molecular interactions is paramount for advancing novel strategies aimed at modulating the immune response against cancer.
PB MDPI
YR 2024
FD 2024
LK https://hdl.handle.net/10630/37199
UL https://hdl.handle.net/10630/37199
LA eng
NO Burgos-Molina, A.M.; Téllez Santana, T.; Redondo, M.; Bravo Romero, M.J. The Crucial Role of Inflammation and the Immune System in Colorectal Cancer Carcinogenesis: A Comprehensive Perspective. Int. J. Mol. Sci. 2024, 25, 6188. https://doi.org/10.3390/ijms25116188
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 4 mar 2026