RT Journal Article
T1 Clinical Manifestations of COVID-19 in the Feet: A Review of Reviews
A1 Jiménez-Cebrián, Ana María
A1 Castro-Méndez, Aurora
A1 Garcia-Podadera, Blanca
A1 Romero-Galisteo, Rita Pilar
A1 Medina-Alcántara, Francisco Miguel
A1 García-Payá, Irene
A1 Páez-Moguer, Joaquín
A1 Córdoba-Fernández, Antonio
K1 COVID-19 - Efectos fisiológicos
AB Abstract: There is a lack of scientific evidence about the severe acute respiratory syndrome coronavirus2 (SARS-CoV-2). The clinical manifestations are not thoroughly understood; classically, thevirus manifests itself at the pulmonary level but can manifest at other levels. To the best of ourknowledge, systematic reviews and non-systematic reviews about COVID-19 symptoms in the feethave not been published. The aim of this review of reviews was to analyze and synthesize thepublished reviews on manifestations of COVID-19 at the foot level. Methods: a review of reviewswas conducted; the eligibility criteria included studies published in English or Spanish, involvingchildren and adults with COVID-19, and reporting foot manifestations. PubMed, SciELO, ScienceDirect, Cochrane Database of Systematic Review, and Google Scholar were analyzed. Two authorsindependently performed the screening and quality assessment of the studies with AMSTAR 1,and finally, nine reviews were analyzed (one systematic and eight narratives studies). The mainclinical manifestations at the foot level in patients with COVID-19 were vascular (edema, exanthems,chilblains, ischemia, and distal necrosis), dermatological (vesicular, maculopapular, papulosquamous,urticarial skin breakouts, and recurrent herpes), and neurological (muscular weakness in lower limbs,paresis, areflexias, ataxia, and difficulty walking). Erythema pernio or “COVID toes” was shown asthe most characteristic lesion of this disease, especially in asymptomatic children and young people,so this typical manifestation may be considered important in patients who are positive for COVID-19.This finding does not allow for strong conclusions due to the scarce literature and methodologicalquality in this regard. Future studies are necessary.
PB MDPI
YR 2021
FD 2021
LK https://hdl.handle.net/10630/33792
UL https://hdl.handle.net/10630/33792
LA eng
NO Jimenez-Cebrian, A.M.; Castro-Mendez, A.; García-Podadera, B.; Romero-Galisteo, R.; Medina-Alcántara, M.; Garcia-Paya, I.; Páez-Moguer, J.; Córdoba-Fernández, A. Clinical Manifestations of COVID-19 in the Feet: A Review of Reviews. J. Clin. Med. 2021, 10, 2201. https://doi.org/10.3390/jcm10102201
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026