RT Journal Article
T1 Design optimization of a 3-stage membrane cascade for oligosaccharides purification using mixed integer non-linear programming.
A1 Rizki, Zulhaj
A1 Janssen, Anja E.M.
A1 Hendrix, Eligius María Theodorus
A1 van der Padt, Albert
A1 Boom, Remko M.
A1 Claassen, G.D.H.
K1 Programación no lineal
AB Inhomogeneous membrane cascade systems have been utilized to purify fructooligosaccharides (FOS).Such a process allows a different setup at every stage of the cascade. Varying the setup at every stage implies an optimization problem related to the selection of the membrane and combinations of operating conditions. This paper solves the optimization problem for an inhomogeneous 3-stage membrane cas- cade and uses the solution as a design guideline. The optimization problem in the 3-stage membrane cas- cade design has been formulated as a mixed integer, non-linear programming model and solved using the global optimization solver, BARON. By maximizing the yield repetitively with varying purity require- ments, a frontier curve has been constructed. The frontier curve was mapped showing the window of operation. The map guides towards the setup that promotes higher permeation in the feed stage when we switch from high yield to high purity. On the other hand, the setup selection at the bottom stage does not show a clear switch, which indicates that the selection at this stage is less critical.
YR 2020
FD 2020
LK https://hdl.handle.net/10630/35167
UL https://hdl.handle.net/10630/35167
LA eng
NO Rizki, Z.,  Janssen, A.E.M.,  Hendrix, E.M.T.,  van  der  Padt, A., Boom, R.M. and Claassen, G.D.H. (2021), Design optimization of a 3-stage membrane cascade for oligosaccharides purification using mixed integer non-linear programming, Chemical  Engineering  Science,  231, 116275
NO Funding from the Spanish Ministry (RTI2018-095993-B-I00), in part financed by the European Regional Development Fund (ERDF) is also acknowledged.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026