RT Journal Article
T1 S- and N-doped carbon quantum dots: Surface chemistry dependent antibacterial activity.
A1 Travlou, Nikolina
A1 Giannakoudakis, Dimitrios
A1 Algarra-González, Manuel
A1 Labella Vera, Alejandro Manuel
A1 Rodríguez-Castellón, Enrique
A1 Bandosz, Teresa J.
K1 Carbono
AB Sulfur and nitrogen-doped carbons quantum dots (S-CQDs and N-CQDs) were obtained using a simplehydrothermal treatment of S- or N-containing organic compounds/polymers. They were evaluated fortheir bactericidal activity against representative Gram-negative (Escherichia coli, CECT 831) and Grampositive(Bacillus subtilis subsp. subtilis 168) bacterial strains, using a qualitative estimation approach.Quantitative tests revealed greater effectiveness of N-CQDs compared to S-CQDs. The bactericidal activityof the dots was linked to their specific surface chemistry, and their sizes in the range of nanometers. Inthe case of the N-CQDs, amides and amines played the most important role in enhancing bactericidalfunction. They caused a bacterial death which was linked to the electrostatic interactions between theirprotonated forms and the lipids of the bacterial cell membrane. It is also possible that the ability toactivate oxygen species by the CQDs surface played some role. S-CQDs showed a much lower bactericidalactivity compared to that of N-CQDs. These dots (S-CQDS), containing mainly a negatively chargedsurface due to dissociation of sulfonic/carboxylic groups and sulfates, showed a size dependent ratherthan a chemistry dependent (electrostatic interactions) inhibition of the Gram-positive bacterial growth.This is the first study where the role of different heteroatoms incorporated to CQDs is examined in thecontext of the bactericidal activity.
PB Elsevier
YR 2018
FD 2018
LK https://hdl.handle.net/10630/34645
UL https://hdl.handle.net/10630/34645
LA eng
NO Nikolina A. Travlou, Dimitrios A. Giannakoudakis, Manuel Algarra, Alejandro M. Labella, Enrique Rodríguez-Castellón, Teresa J. Bandosz, S- and N-doped carbon quantum dots: Surface chemistry dependent antibacterial activity, Carbon, Volume 135, 2018, Pages 104-111, ISSN 0008-6223, https://doi.org/10.1016/j.carbon.2018.04.018. (https://www.sciencedirect.com/science/article/pii/S0008622318303634)
NO https://v2.sherpa.ac.uk/id/publication/16741
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 4 mar 2026