RT Conference Proceedings T1 Biosensor fotónico integrado con capacidad de discriminación por capas. A1 Sánchez-Ramírez, Ana A1 Wanguemert-Pérez, Juan Gonzalo A1 De-Oliva-Rubio, José A1 Luque-González, José Manuel A1 Godoy-Rubio, Rafael A1 Ortega-Moñux, Alejandro A1 Halir, Robert A1 Leuermann, Jonas A1 Molina-Fernández, Íñigo K1 Biosensores K1 Fotónica AB Photonic integrated biosensors have emerged as a highly attractive alternative for biomarker detection in applications ranging from clinical diagnosis to food quality monitoring. Detecting specific target and differentiating them from interfering background effects is a crucial but challenging task nowadays. In this work, a complete system based on a dual polarization Mach-Zehnder interferometer with coherent detection is proposed to identify refractive index changes from different layers above the waveguide surface, herein, improving sensor specificity. To achieve this, a mathematical model is developed based on performing simultaneous measurements with two different polarization states. Simulation results show values of the limit of detection for each layer comparable to those reported in the state of the art. PB XXXVIII Simposio Nacional de la Unión Científica Internacional de Radio YR 2023 FD 2023 LK https://hdl.handle.net/10630/27631 UL https://hdl.handle.net/10630/27631 LA spa NO Este trabajo ha sido financiado por el Ministerio de Ciencia e Innovación (PRE2020-096438, PID2019-106747RB-I00); la Consejería de Economía, Conocimiento, Empresas y Universidad (P18-RT-793); la Consejería de Salud y Familias, (PIN-0113-2020); la Consejería de Universidad, Investigación e Innovación (PAIDI 2020, AT21_00153) y la Universidad de Málaga (Campus de Excelencia Internacional Andalucía Tech.) DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026