RT Journal Article
T1 ANF Therapy® for pain management. Feasibility, satisfaction, perceived symptom reduction and side effects. A real-world multisite observational study
A1 De la Vega, Rocío
A1 Heinisuo, Irina A.
A1 López-Martínez, Alicia Eva
A1 Serrano-Ibáñez, Elena Rocío
A1 Ruiz-Párraga, Gema Teresa
A1 Ramírez-Maestre, María del Carmen
A1 Esteve-Zarazaga, Rosa
K1 Dolor - Aspectos psicológicos
K1 Medicina - Innovaciones tecnológicas
AB [Purpose] Non-invasive and drug-free interventions for pain are being developed. One of them is ANF(which stands for “Amino Neuro Frequency”) Therapy®, which consists in the application of carbonized metal deviceson a patient’s skin. We aimed to: 1) test perceived changes in pain intensity after ANF application, 2) recordfrequency and severity of side effects, 3) assess clinician and patient satisfaction, 4) explore effects on swelling andrange of motion (ROM). [Participants and Methods] In this real-world multisite observational study, N=113 physicaltherapists in 45 countries, applied ANF to N=1,054 patients (Mage=45.2, 56.2% female) with pain complaints.Demographic data, pain intensity (NRS-11), effects of ANF on swelling and ROM, clinician and patient satisfactionand side effects were collected. [Results] Main pain locations were: low back (14.9%), knee (12.4%), neck (10%),and shoulder (9.6%). Pre-treatment pain intensity was high (Mean=7.6, SD=1.9). It significantly decreased posttreatment(Mean=3.1, SD=2.0), t(1053)=7.25, with a large effect size (Cohen’s d=2.2). Swelling decreased and ROMincreased. Average satisfaction with ANF was 92/100. Patients often experienced mild side effects (42.3%): drymouth, headache and fatigue. [Conclusion] Results show large effect sizes, high satisfaction, and mild and shorttermside effects. This is very promising but should be interpreted with caution considering the study limitations.
YR 2023
FD 2023-12-01
LK https://hdl.handle.net/10630/30811
UL https://hdl.handle.net/10630/30811
LA eng
NO de la Vega, R., Heinisuo, I. A., López-Martínez, A. E., Serrano-Ibáñez, E. R., Ruíz-Párraga, G. T., Ramírez-Maestre, C., & Esteve, R. (2023). ANF therapy® for pain management, feasibility, satisfaction, perceived symptom reduction and side effects: a real-world multisite observational study. Journal of Physical Therapy Science, 35(12), 768–776.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026