RT Journal Article
T1 Summer and spring elbow rashes is a variant of polymorphous light eruption: confirmation by photoprovocation and histopathology in a series of five cases
A1 De-Gálvez-Aranda, María Victoria
A1 Castillo-Muñoz, Rosa María
A1 López-Navarro, Norberto
A1 López Jiménez, Patricio
A1 Navarrete-de-Gálvez, Enrique
A1 Herrera-Acosta, Enrique
A1 Aguilera-Arjona, José
K1 Piel - Enfermedades
AB Background: Summer and spring eruptions on the elbows are a variantof polymorphous light eruption described on clinical and histopathologicalgrounds; however, to our knowledge, they have not been confirmed byphotobiological studies.Objective: Based on photobiological studies, this study aimed to demonstrate theinvolvement of ultraviolet-A (UVA) radiation in this variant of polymorphous lighteruption occurring exclusively on the elbows.Methods: A series of five patients with polymorphous light eruption lesionson the elbows were included in our study. All patients underwent phototestingand photoprovocation of the skin lesions after exposure to a UVA light source[Philips UVA HPA lamp (400 W)]. All patients underwent punch biopsy andhistopathological and immunohistochemical studies with anti-CD123.Results: In all the cases, UVA irradiation caused the appearance of skin lesionson the elbows with characteristic polymorphous light eruption. Histological datashowed edema in the superficial dermis and a perivascular lymphocytic infiltratecompatible with polymorphous light eruption. Immunohistochemical staining forCD1-23 showed negative results.Conclusions: For the first time, photobiological photoprovocation studiesdemonstrated that repeated exposure to UVA radiation leads to the generationof skin lesions on the elbows, which are clinically and histologically consistentwith summer and spring eruptions, confirming that elbow rash is a variant ofpolymorphous light eruption
PB Frontiers
YR 2023
FD 2023-10-19
LK https://hdl.handle.net/10630/30229
UL https://hdl.handle.net/10630/30229
LA eng
NO de Gálvez MV, Castillo-Muñoz RM, López-Navarro N, López-Jiménez P, Navarrete-de Gálvez E, Bosch-García R, Herrera-Acosta E, Aguilera J. Summer and spring elbow rashes is a variant of polymorphous light eruption: confirmation by photoprovocation and histopathology in a series of five cases. Front Med (Lausanne). 2023 Oct 19;10:1260514. doi: 10.3389/fmed.2023
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 ene 2026