RT Journal Article T1 The Benefits of a Therapeutic Exercise and Educational Intervention Program on Central Sensitization Symptoms and Pain-Related Fear Avoidance in Breast Cancer Survivors A1 Gutiérrez-Sánchez, Daniel A1 Pajares-Hachero, Bella I. A1 Trinidad-Fernández, Manuel A1 Escriche-Escuder, Adrián A1 Iglesias-Campos, Marcos A1 Bermejo-Pérez, María José A1 Alba-Conejo, Emilio A1 Roldán-Jiménez, Cristina A1 Cuesta-Vargas, Antonio K1 Ejercicios terapéuticos K1 Mamas -- Cáncer AB Background:Central sensitization symptoms and pain-related fear avoidance are two common problems in breast cancer survivors. Non-pharmacologic interventions such as therapeutic exercise and patient education can be effective in this population.Aims:This study aimed to: (1) analyze the benefits of a therapeutic exercise and educational program on central sensitization symptoms and pain-related fear avoidance in breast cancer survivors, and (2) explore the association between pain-related fear avoidance and central sensitization symptoms.Design:A single group pre–post intervention study was conducted.Methods:Patients were recruited from the service of Medical Oncology of the University Clinical Hospital Virgen de la Victoria, in Málaga (Spain). The intervention consisted of a therapeutic exercise and educational program that lasted 12 weeks, twice a week, for 1 hour. Two instruments were used: the Spanish version of the Central Sensitization Inventory and the Spanish Fear Avoidance Components Scale.Results:A total of 82 breast cancer survivors participated in the study. Pre–post change on Central Sensitization Inventory was statistically significant (p = .007). There was a trend towards a significant difference for the Spanish Fear Avoidance Components Scale (p = .062). There was a statistically significant correlation between pain-related fear avoidance and central sensitization symptoms (r = 0.536, p < .001).Conclusions:The current study has provided preliminary evidence on the benefits of this intervention in pain-related fear avoidance and central sensitization symptoms in breast cancer survivors. The Spanish version of the Central Sensitization Inventory and the Spanish Fear Avoidance Components Scale demonstrated responsiveness to change. PB Elsevier YR 2022 FD 2022-03-09 LK https://hdl.handle.net/10630/26524 UL https://hdl.handle.net/10630/26524 LA eng NO Gutiérrez-Sánchez, D., Pajares-Hachero, B. I., Trinidad-Fernández, M., Escriche-Escuder, A., Iglesias-Campos, M., Bermejo-Pérez, M. J., ... & Cuesta-Vargas, A. (2022). The Benefits of a Therapeutic Exercise and Educational Intervention Program on Central Sensitization Symptoms and Pain-Related Fear Avoidance in Breast Cancer Survivors. Pain Management Nursing, 23(4), 467-472. NO This research project was partially funded by Contract N° PS16060 in IBIMA between Novartis-IBIMA (Traslation Research in Cancer B-01 & Clinimetric F-14) for the physiotherapist of the assessment /// Funding for open access charge: Universidad de Málaga / CBUA DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 26 ene 2026