RT Journal Article T1 Impact of a nurse-led intervention on quality of life in patients with chronic non-malignant pain: An open randomized controlled trial A1 Morales-Fernández, Ángeles A1 Jiménez Martín, José Manuel A1 Morales-Asencio, José Miguel A1 Vergara Romero, Manuel A1 Mora-Banderas, Ana María A1 Aranda-Gallardo, Marta A1 Canca-Sánchez, José Carlos K1 Tratamiento paliativo AB Aims: To determine the effect of a comprehensive nurse-led programme for patientswith chronic non-malignant pain, on quality of life, level of pain, anxiety, and depression,as primary outcomes and patients' satisfaction as a secondary end point.Design: An open-label randomized controlled trial was carried out.Methods: The experimental group received both a nurse-led intervention on healthylifestyles, education on self-esteem, pain awareness, communication, and relaxationtechniques. The control group received usual care. Quality of life, level of pain, anxiety,and depression were the main outcomes. Data were obtained at baseline, immediatelyafter the intervention, and 6 and 9 months. The study was carried out from2015–2017.Results: The sample was composed of 279 patients. At 9 months, the effect size(non-parametric effect size statistic A) favoured the intervention group for SF-36mental health score (A = 0.79; 95% CI: 0.73–0.85), anxiety (A = 0.58; 95% CI: 0.51–0.65), pain intensity (A = 0.57; 95% CI: 0.51–0.64), and depression (A = 0.58; 95% CI:0.51–0.65). Smaller differences were found on physical scores between the interventionand the usual care group. Patients showed a high level of satisfaction with theintroduced intervention.Conclusion: A comprehensive nurse-led programme for patients with chronic nonmalignantpain has a positive impact on their quality of life, level of pain, and mentalhealth.Impact: Studies have reported that the problem of chronic pain is not optimally controlled.A structured nurse-led programme has been tested to facilitate healthy behavioursto help patients manage their chronic pain and to provide them with thenecessary tools for their self-care. This nurse-led intervention improved their mentalhealth and decreased their level of pain.K E Y W O R D Sanxiety, chronic pain, depression, health promotion/health education, nursing, painmanagement, patient satisfaction, quality of life PB Wiley Online Library YR 2020 FD 2020-09-30 LK https://hdl.handle.net/10630/37477 UL https://hdl.handle.net/10630/37477 LA eng NO Morales-Fernández Á, Jimenez-Martín JM, Morales-Asencio JM, et al. Impact of a nurse-led intervention on quality of life in patients with chronic non-malignant pain: An open randomized controlled trial. J Adv Nurs. 2021; 77: 255–265. https://doi.org/10.1111/jan.14608 DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 25 ene 2026