RT Journal Article
T1 Fish skin grafts versus standard of care on wound healing of chronic diabetic foot ulcers: a systematic review and meta-analysis
A1 Ruiz-Muñoz, María
A1 Martínez-Barrios, Francisco-Javier
A1 Cervera-Garvi, Pablo
A1 Lópezosa-Reca, Eva
A1 Marchena-Rodríguez, Ana José
K1 Diabetes - Complicaiones y secuelas
K1 Piel - Injertos
AB This study will explore the effectiveness of fish skin grafts (FSG) in ulcer healing in diabetic foot disease compared to standard of care (SOC).The systematic review and meta-analysis were performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standard. The electronic databases of PubMed, EMBASE, and Web of Science (WoS) internet were searched for the outcome rate of complete ulcer healing. The risk of bias assessment was conducted using the tool recommended by the Cochrane Collaboration. Statistical analysis included the individual and combined result of the studies, heterogeneity test, the effect size, sensitivity analysis, and publication bias tests.Five randomised controlled trials (RCTs) with a total of 411 patients were included in this study. This meta-analysis showed a higher rate of complete ulcer healing in groups receiving fish skin grafts (OR = 3.34, 95% CI 2.14–5.20, p < 0.01, I2 = 0%) compared to control groups.Fish skin grafts have been shown to be more effective for achieving complete ulcer healing compared to current conventional treatments in diabetic foot disease.
PB Elsevier
YR 2024
FD 2024
LK https://hdl.handle.net/10630/31369
UL https://hdl.handle.net/10630/31369
LA eng
NO Maria Ruiz-Muñoz, Francisco-Javier Martinez-Barrios, Pablo Cervera-Garvi, Eva Lopezosa-Reca, Ana J. Marchena-Rodriguez, Fish skin grafts versus standard of care on wound healing of chronic diabetic foot ulcers: A systematic review and meta-analysis, Primary Care Diabetes, Volume 18, Issue 3, 2024, Pages 291-298, ISSN 1751-9918, https://doi.org/10.1016/j.pcd.2024.03.008
NO Funding for open access charge: Universidad de Málaga / CBUA
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026