RT Journal Article T1 Potential probiotic salami with dietary fiber modulates metabolism and gut microbiota in a human intervention study. A1 Pérez-Burillo, Sergio A1 Pastoriza, Silvia A1 Gironés, Amadeo A1 Avellaneda, Antonio A1 Francino, Maria Pilar A1 Rufián-Henares, José Ángel K1 Fibra en nutrición K1 Flora intestinal - Investigación AB A human intervention in 24 healthy volunteers was performed to test the potential health benefits of a fermented salami with a probiotic Lactobacillus rhamnosus HN001 and added citrus fiber. Anthropometric measurements and blood biochemistry did not show any significant differences between pre- and post-intervention during 4 weeks with a daily intake of 30 g of salami, neither with regular salami (control group) nor with reformulated salami (intervention group). However, the inflammatory markers CRP and TNFα decreased significantly after intervention, suggesting a less inflammatory environment after reformulated salami consumption. Antioxidant plasmatic markers also improved within the intervention group. Butyrate production was significantly increased after reformulated salami consumption. Gut microbiota community structure, however, was not significantlyshaped by neither regular nor reformulated salami. After the intervention with probiotic salami, L. rhamnosus was detected by quantitative polymerase chain reaction (qPCR) in all samples of the intervention group but not in the control group, showing probiotic effect. PB Elsevier YR 2020 FD 2020 LK https://hdl.handle.net/10630/32380 UL https://hdl.handle.net/10630/32380 LA eng NO S. Pérez-Burillo, S. Pastoriza, A. Gironés, A. Avellaneda, M. Pilar Francino, J.A. Rufián-Henares, Potential probiotic salami with dietary fiber modulates metabolism and gut microbiota in a human intervention study, Journal of Functional Foods, Volume 66, 2020, 103790, ISSN 1756-4646, https://doi.org/10.1016/j.jff.2020.103790 NO This trial was supported by project AVANZA-S from the Spanish Centre for the Development of Industrial Technology (CDTI). It was also supported by a Spanish predoctoral fellowship F.P.U. (ref.: FPU14/01192) for S. Perez-Burillo from the Spanish Government. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 23 ene 2026