RT Journal Article T1 Oxidative stress and antioxidant parameters in patients with major depressive disorder compared to healthy controls before and after antidepressant treatment: results from a meta-analysis. A1 Jiménez-Fernández, S. A1 Gurpegui, Manuel A1 Dí­az-Atienza, Francisco A1 Pérez-Costillas, Lucía María A1 Gerstenberg, Miriam A1 Correll, Christoph U. K1 Desórdenes mentales K1 Depresión mental K1 Antidepresivos K1 Estrés oxidativo AB Objective: To investigate the role of oxidative stress and antioxidants in depression.Data Sources: We searched the literature without language restrictions through MEDLINE/PubMed, Cochrane Library, Fisterra, and Galenicom from database inception until December 31, 2013, supplemented by a hand search of relevant articles. Search terms included (1) oxidative stress, antioxidant*, nitrosative stress, nitrative stress, nitro-oxidative stress, free radical*, and names of individual oxidative stress markers/antioxidants and (2) depression and related disorders and antidepressant.Study Selection: Included were studies in patients with depression comparing antioxidant or oxidative stress markers with those in healthy controls before and after antidepressant treatment.Data Extraction: Two authors independently extracted the data for antioxidant or oxidative stress markers. Standardized mean differences (SMDs) ± 95% confidence intervals (CIs) for results from ≥ 3 studies were calculated. YR 2015 FD 2015-12-23 LK https://hdl.handle.net/10630/29937 UL https://hdl.handle.net/10630/29937 LA eng NO Jiménez-Fernández, S., Gurpegui, M., Díaz-Atienza, F., Pérez-Costillas, L., Gerstenberg, M., & Correll, C. U. (2015). Oxidative Stress and Antioxidant Parameters in Patients With Major Depressive Disorder Compared to Healthy Controls Before and After Antidepressant Treatment. The Journal of Clinical Psychiatry, 76(12), 1658–1667. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026