RT Journal Article
T1 Relationship between quadriceps femoris echotexture biomarkers and muscle strength and physical function in older adults with heart failure with preserved ejection fraction
A1 Fuentes-Abolafio, Iván José
A1 Ricci, Michele
A1 Bernal López, María Rosa
A1 Gómez-Huelgas, Ricardo
A1 Cuesta-Vargas, Antonio
A1 Pérez-Belmonte, Luis Miguel
K1 Músculos - Potenciación
K1 Ancianos
AB Background: Muscle wasting is pronounced in patients with heart failure with preserved ejection fraction(HFpEF). The quadriceps femoris echotexture biomarkers assessed by ultrasound (US) have not been studied inthese patients.Objective: To describe echotexture biomarkers assessed by the US and to assess their relationship with sex, age,body mass index (BMI), self-reported outcomes, muscle strength and physical function in older adults withHFpEF.Methods: A cross-sectional study was conducted. Patients 70 years and older with HFpEF were included. The sex,age, BMI, and self-reported outcomes were collected. The US assessed muscle and subcutaneous fat tissuecontrast, correlation, energy, homogeneity, and entropy at rest and maximal voluntary isometrical contraction(MVIC). The six-minute walk test (6MWT), the short physical performance battery (SPPB), the timed up and gotest (TUG), the usual pace gait speed test (UGS), and the fast pace gait speed test (FGS) were used to assessphysical function. The five-repetitions sit-to-stand test (5-STS) was performed to assess muscle strength. BivariantPearson correlations and subsequent multivariate linear regression analyses were conducted.Results: Seventy-two older adults with HFpEF [81.06 years, 29.13 BMI, and 55.60% females] were recruited. Inwomen, relaxed and MVIC muscle energy and entropy explained 35.40% of the TUG variance; relaxed muscleentropy and MVIC muscle energy shared 24.00% of the UGS variance; relaxed and MVIC muscle entropy, MVICmuscle contrast and MVIC muscle energy explained 32.60% of the FGS variance, adjusted all the models by ageand BMI.
PB Elsevier
YR 2024
FD 2024-06-01
LK https://hdl.handle.net/10630/30941
UL https://hdl.handle.net/10630/30941
LA eng
NO Iván José Fuentes-Abolafio, Michele Ricci, María Rosa Bernal-López, Ricardo Gómez-Huelgas, Antonio Ignacio Cuesta-Vargas, Luis Miguel Pérez-Belmonte, Relationship between quadriceps femoris echotexture biomarkers and muscle strength and physical function in older adults with heart failure with preserved ejection fraction, Experimental Gerontology, Volume 190, 2024, 112412, ISSN 0531-5565, https://doi.org/10.1016/j.exger.2024.112412
NO Funding for open access charge: Universidad de málaga /CBUA
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 21 ene 2026