RT Journal Article
T1 Fish skin grafts versus standard of care on wound healing of chronic diabetic foot ulcers: A systematic review and meta-analysis
A1 Lopezosa Reca, Eva
A1 Martinez Barrios, Francisco Javier
A1 Ruiz Muñoz, Maria
A1 Cervera Garvi, Pablo
A1 Marchena Rodriguez, Ana
K1 Diabetes - Complicaciones y secuelas
AB Introduction: This study will explore the effectiveness of fish skin grafts (FSG) in ulcer healing in diabetic footdisease compared to standard of care (SOC).Methods: The systematic review and meta-analysis were performed following the Preferred Reporting Items forSystematic Reviews and Meta-Analyses (PRISMA) standard. The electronic databases of PubMed, EMBASE, andWeb of Science (WoS) internet were searched for the outcome rate of complete ulcer healing. The risk of biasassessment was conducted using the tool recommended by the Cochrane Collaboration. Statistical analysisincluded the individual and combined result of the studies, heterogeneity test, the effect size, sensitivity analysis,and publication bias tests.Results: Five randomised controlled trials (RCTs) with a total of 411 patients were included in this study. Thismeta-analysis showed a higher rate of complete ulcer healing in groups receiving fish skin grafts (OR = 3.34,95% CI 2.14–5.20, p < 0.01, I2 = 0%) compared to control groups.Conclusion: Fish skin grafts have been shown to be more effective for achieving complete ulcer healing comparedto current conventional treatments in diabetic foot disease.
PB Elsevier
YR 2024
FD 2024-06
LK https://hdl.handle.net/10630/36660
UL https://hdl.handle.net/10630/36660
LA eng
NO Ruiz-Muñoz, M., Martinez-Barrios, F. J., Cervera-Garvi, P., Lopezosa-Reca, E., & Marchena-Rodriguez, A. J. (2024). Fish skin grafts versus standard of care on wound healing of chronic diabetic foot ulcers: A systematic review and meta-analysis. Primary care diabetes, 18(3), 291–298.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026