RT Journal Article T1 The impact of depression symptoms in patients with Parkinson's disease: a novel case-control investigation A1 Jiménez-Cebrián, Ana María A1 Becerro-de-Bengoa-Vallejo, Ricardo A1 Losa-Iglesias, Marta Elena A1 López-López, Daniel A1 Calvo-Lobo, César A1 Palomo-López, Patricia A1 Romero-Morales, Carlos A1 Navarro-Flores, Emmanuel María K1 Parkinson, Enfermedad de - Aspectos psicológicos AB Parkinson’s disease is a common neurodegenerative disease and it is known to cause motordisturbances associated with musculoskeletal problems of the locomotor apparatus, and non-motorsymptoms, that are believed to have a harmful effect on health, social functioning and mobility. Theaim of this study was to evaluate depression in patients with Parkinson’s Disease (PD) comparedto subjects who do not have it. The sample consisted of 124 participants (mean age 69.18 ± 9.12).Patients with PD were recruited from a center of excellence for Parkinson’s disease (cases n = 62)and healthy subjects without PD from their relatives and caregivers (control n = 62). The Spanishversion of Beck’s Depression Inventory (BDI) scores and categories were collected. A clear statisticallysignificant difference (p < 0.05) was evident in the BDI scores between both groups. Parkinson’spatients presented worse results on the BDI = 15.48 ± 7.24 points compared to healthy subjects withBDI = 7.03 ± 6.99 points. Regarding BDI categories, there were statistically significant differences(p < 0.001) for the greater BDI categories in the Parkinson’s group compared with healthy subjects.The depression represents an important potential risk for increased symptoms and negative impactamong patients with PD compared with healthy subjects. PB MDPI YR 2021 FD 2021 LK https://hdl.handle.net/10630/39132 UL https://hdl.handle.net/10630/39132 LA eng NO Jiménez-Cebrián AM, Becerro-de-Bengoa-Vallejo R, Losa-Iglesias ME, López-López D, Calvo-Lobo C, Palomo-López P, Romero-Morales C, Navarro-Flores E. The Impact of Depression Symptoms in Patients with Parkinson's Disease: A Novel Case-Control Investigation. Int J Environ Res Public Health. 2021 Mar 1;18(5):2369. doi: 10.3390/ijerph18052369. PMID: 33804349; PMCID: PMC7967746. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 21 ene 2026