RT Journal Article
T1 Energy Balance and Risk of Mortality in Spanish Older Adults
A1 Camille Lassale, 
A1 Álvaro Hernáez, 
A1 Estefanía Toledo, 
A1 Olga Castañer, 
A1 José V Sorlí, 
A1 Jordi Salas-Salvadó, 
A1 Ramon Estruch, 
A1 Emilio Ros, 
A1 Ángel M Alonso-Gómez, 
A1 José Lapetra, 
A1 Cueto-Galán, Raquel
A1 Fiol, Miquel
A1 Serra-Majem, Lluis
A1 Pinto, Xabier
A1 Gea, Alfredo
A1 Corella, Dolores
A1 Babio, Nancy
A1 Fitó, Montserrat
A1 Schröder., Helmut
K1 Mortalidad
K1 Ejercicio físico
AB This study from the PREDIMED trial examined the relationship between energy balance (deficit or surplus) and mortality risks, including all-cause, cardiovascular, and cancer mortality. It followed 7,119 older participants (mean age 67 years) for a median of 4.8 years. Energy intake was assessed using a food frequency questionnaire, and theoretical energy expenditure (TEE) was estimated based on demographic and physical activity data.Results showed that an energy surplus (intake exceeding estimated needs) was linked to an increased risk of mortality, particularly cardiovascular death. For every 10% surplus, the hazard ratio (HR) for mortality increased by 1.10, and for cardiovascular mortality, by 1.26. Conversely, an energy deficit did not show a protective effect on mortality. Additionally, increments in energy intake over time correlated with a higher risk of all-cause mortality, but reductions in intake did not decrease mortality risk.The study concludes that in older adults following a Mediterranean diet, an energy surplus or increases in energy intake are associated with higher mortality risks, especially cardiovascular. Conversely, energy deficits or reduced intake do not lower mortality risks.
PB Nutrients
YR 2021
FD 2021-05-04
LK https://hdl.handle.net/10630/35554
UL https://hdl.handle.net/10630/35554
LA eng
NO Lassale C, Hernáez Á, Toledo E, Castañer O, Sorlí JV, Salas-Salvadó J, Estruch R, Ros E, Alonso-Gómez ÁM, Lapetra J, Cueto R, Fiol M, Serra-Majem L, Pinto X, Gea A, Corella D, Babio N, Fitó M, Schröder H. Energy Balance and Risk of Mortality in Spanish Older Adults. Nutrients. 2021 May 4;13(5):1545. doi: 10.3390/nu13051545. PMID: 34064328; PMCID: PMC8147789
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026