RT Journal Article
T1 Maximal Respiratory Pressure Reference Equations in Healthy Adults and Cut-off Points for Defining Respiratory Muscle Weakness.
A1 Lista-Paz, Ana
A1 Langer, Daniel
A1 Barral-Fernández, Margarita
A1 Quintela-del-Río, Alejandro
A1 Gimeno-Santos, Elena
A1 Arbillaga-Etxarri, Ane
A1 Torres-Castro, Rodrigo
A1 Vilaró-Casamitjana, Jordi
A1 Varas-de-la-Fuente, Ana-B.
A1 Serrano-Veguillas, Cristina
A1 Bravo-Cortés, Pilar
A1 Martín-Cortijo, Concepción
A1 García-Delgado, Esther
A1 Herrero-Cortina, Beatriz
A1 Valera, José-Luis
A1 Fregonezi, Guilherme-A.-F.
A1 González-Montañez, Carolina
A1 Martín-Valero, Rocío
A1 Francín-Gallego, Marina
A1 Sanesteban-Hermida, Yolanda
A1 Giménez-Moolhuyzen, Esther
A1 Álvarez-Rivas, Jorge
A1 Ríos-Cortes, Antonio T.
A1 Souto-Camba, Sonia
A1 González-Doniz, Luz
A2 Vilaró-Casamitjana, Jordi
K1 Respiración
K1 Músculos respiratorios
K1 Epidemiología
K1 Aparato respiratorio
AB IntroductionMaximal inspiratory and expiratory pressures (PImax/PEmax) reference equations obtained in healthy people are needed to correctly interpret respiratory muscle strength. Currently, no clear cut-off points defining respiratory muscle weakness are available. We aimed to establish sex-specific reference equations for PImax/PEmax in a large sample of healthy adults and to objectively determine cut-off points for respiratory muscle weakness.MethodsA multicentre cross-sectional study was conducted across 14 Spanish centres. Healthy non-smoking volunteers aged 18–80 years stratified by sex and age were recruited. PImax/PEmax were assessed using uniform methodology according to international standards. Multiple linear regressions were used to obtain reference equations. Cut-off points for respiratory muscle weakness were established by using T-scores.ResultsThe final sample consisted of 610 subjects (314 females; 48 [standard deviation, SD: 17] years). Reference equations for PImax/PEmax included body mass index and a squared term of the age as independent variables for both sexes (p < 0.01). Cut-off points for respiratory muscle weakness based on T-scores ≥2.5 SD below the peak mean value achieved at a young age were: 62 and 83 cmH2O for PImax and 81 and 109 cmH2O for PEmax in females and males, respectively.ConclusionThese reference values, based on the largest dataset collected in a European population to date using uniform methodology, help identify cut-off points for respiratory muscle weakness in females and males. These data will help to better identify the presence of respiratory muscle weakness and to determine indications for interventions to improve respiratory muscle function.
PB Elsevier
YR 2023
FD 2023-12
LK https://hdl.handle.net/10630/35425
UL https://hdl.handle.net/10630/35425
LA eng
NO Ana Lista-Paz, Daniel Langer, Margarita Barral-Fernández, Alejandro Quintela-del-Río, Elena Gimeno-Santos, Ane Arbillaga-Etxarri, Rodrigo Torres-Castro, Jordi Vilaró Casamitjana, Ana B. Varas de la Fuente, Cristina Serrano Veguillas, Pilar Bravo Cortés, Concepción Martín Cortijo, Esther García Delgado, Beatriz Herrero-Cortina, José Luis Valera, Guilherme A.F. Fregonezi, Carolina González Montañez, Rocío Martín-Valero, Marina Francín-Gallego, Yolanda Sanesteban Hermida, Esther Giménez Moolhuyzen, Jorge Álvarez Rivas, Antonio T. Ríos-Cortes, Sonia Souto-Camba, Luz González-Doniz, Maximal Respiratory Pressure Reference Equations in Healthy Adults and Cut-off Points for Defining Respiratory Muscle Weakness, Archivos de Bronconeumología, Volume 59, Issue 12, 2023, Pages 813-820, ISSN 0300-2896, https://doi.org/10.1016/j.arbres.2023.08.016
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 22 ene 2026