RT Journal Article
T1 Zebrafish Models for Human Skeletal Diseases
A1 Mari-Beffa, Manuel
A1 Mesa-Román, Ana Belén
A1 Durán-Jimenez, Iván Jesús
K1 Displasia ósea - Modelos animales
K1 Huesos - Enfermedades
AB In 2019, the Nosology Committee of the International Skeletal Dysplasia Society provided an updated version of the Nosology and Classification of Genetic Skeletal Disorders. This is a reference list of recognized diseases in humans and their causal genes published to help clinician diagnosis and scientific research advances. Complementary to mammalian models, zebrafish has emerged as an interesting species to evaluate chemical treatments against these human skeletal disorders. Due to its versatility and the low cost of experiments, more than 80 models are currently available. In this article, we review the state-of-art of this “aquarium to bedside” approach describing the models according to the list provided by the Nosology Committee. With this, we intend to stimulate research in the appropriate direction to efficiently meet the actual needs of clinicians under the scope of the Nosology Committee
PB Frontiers
YR 2021
FD 2021-08-05
LK https://hdl.handle.net/10630/40109
UL https://hdl.handle.net/10630/40109
LA eng
NO Marí-Beffa M, Mesa-Román AB  and Duran I (2021) Zebrafish Models  for Human Skeletal Disorders.  Front. Genet. 12:675331.  doi: 10.3389/fgene.2021.675331
NO Junta de Andalucía
NO Fundación AHUCE
NO Gobierno Español
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 27 feb 2026