RT Journal Article T1 Genome Editing as a Tool for Fruit Ripening Manipulation A1 Martín-Pizarro, Carmen A1 Posé-Padilla, David K1 Frutas - Maduración K1 Genomas AB Over the last few years, a series of tools for genome editing have been developed, allowing the introduction of precise changes into plant genomes. These have included Zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, which is so far the most successful and commonly used approach for targeted and stable editing of DNA, due to its ease of use and low cost. CRISPR/Cas9 is now being widely used as a new plant breeding technique to improve commercially relevant crop species. Fruit ripening is a complex and genetically controlled developmental process that is essential for acquiring quality attributes of the fruit. Although the number of studies published to date using genome editing tools to molecularly understand or improve fruit ripening is scarce, in this review we discuss these achievements and how genome editing opens tremendous possibilities not only for functional studies of genes involved in fruit ripening, but also to generate non-transgenic plants with an improved fruit quality. PB Frontiers YR 2018 FD 2018-09-25 LK https://hdl.handle.net/10630/23563 UL https://hdl.handle.net/10630/23563 LA eng NO Martín-Pizarro C and Posé D (2018) Genome Editing as a Tool for Fruit Ripening Manipulation. Front. Plant Sci. 9:1415 DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 30 ene 2026