RT Journal Article
T1 Coelomic epithelium-derived cells in visceral morphogenesis
A1 Ariza, Laura
A1 Carmona-Mejías, Rita María
A1 Cañete, Ana
A1 Cano, Elena
A1 Muñoz-Chápuli-Oriol, Ramón
K1 Morfogénesis
AB Coelomic cavities of vertebrates are lined by a mesothelium which develops from the lateral plate mesoderm. During development, the coelomic epithelium is a highly active cell layer, which locally is able to supply mesenchymal cells that contribute to the mesodermal elements of many organs and provide signals which are necessary for their development. The relevance of this process of mesenchymal cell supply to the developing organs is becoming clearer because genetic lineage tracing techniques have been developed in recent years. Body wall, heart, liver, lungs, gonads, and gastrointestinal tract are populated by cells derived from the coelomic epithelium which contribute to their connective and vascular tissues, and sometimes to specialized cell types such as the stellate cells of the liver, the Cajal interstitial cells of the gut or the Sertoli cells of the testicle. In this review we collect information about the contribution of coelomic epithelium derived cells to visceral development, their developmental fates and signaling functions. The common features displayed by all these processes suggest that the epithelial–mesenchymal transition of the embryonic coelomic epithelium is an underestimated but key event of vertebrate development, and probably it is shared by all the coelomate metazoans
PB American Association for Anatomy
YR 2016
FD 2016-03
LK https://hdl.handle.net/10630/36302
UL https://hdl.handle.net/10630/36302
LA eng
NO Ariza, L., Carmona, R., Cañete, A., Cano, E. and Muñoz-Chápuli, R. (2016), Coelomic epithelium-derived cells in visceral morphogenesis. Dev. Dyn., 245: 307-322. https://doi.org/10.1002/dvdy.24373
NO This study was funded by the Spanish Ministry of Economy and Innovation, Junta de Andalucía, and grants from the Instituto de Salud Carlos III co-founded by Fondo Europeo de Desarrollo Regional - FEDER.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026