RT Journal Article
T1 Autologous platelet-rich plasma (APRP) in diabetes foot disease: a meta-analysis
A1 Ruiz-Muñoz, María
A1 Martínez-Barrios, Francisco-Javier
A1 Fernández Torres, Raúl
A1 Lópezosa-Reca, Eva
A1 Marchena-Rodríguez, Ana José
K1 Enfermería
K1 Neuropatías diabéticas - Tratamiento
AB IntroductionThis study will explore the effectiveness of autologous platelet-rich plasma in the treatment of diabetic foot disease compared to conventional treatments, based on the ulcer healing rate.MethodsThe electronic databases of PubMed, EMBASE, and WOS internet were searched. Evaluated outcome rate of complete ulcer healing. Statistical analysis was performed with RevMan 5.0 software and SPSS 25.0.ResultsEleven RCTs with 828 patients were included in this study. The meta-analysis showed a higher complete ulcer healing rate (OR = 3.69, 95 % CI 2.62 to 5.20, P < 0.01, I2 = 0 %) in growth factors based in autologous platelech-rich plasma (aPRP) group compared with control. Mixed evidence was seen for publication bias, but analyses by using the trim-and-fill method did not appreciably alter results.ConclusionAutologous platelet-rich plasma can improve the complete healing rate of the ulcer compared to current conventional treatments in diabetic foot ulcer patients.
PB Elsevier
YR 2024
FD 2024-01-19
LK https://hdl.handle.net/10630/29456
UL https://hdl.handle.net/10630/29456
LA eng
NO Maria Ruiz-Muñoz, Francisco-Javier Martinez-Barrios, Raul Fernandez-Torres, Eva Lopezosa-Reca, Ana Marchena-Rodriguez, Autologous platelet-rich plasma (APRP) in diabetes foot disease: a meta-analysis, Journal of Diabetes and its Complications, Volume 38, Issue 2, 2024, 108690, ISSN 1056-8727, https://doi.org/10.1016/j.jdiacomp.2024.108690
NO Funding for open Access charge: Universidad de Málaga / CBUA
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026