RT Journal Article
T1 Sppdp11 administration in diet modified the transcriptomic response and its microbiota associated in mechanically induced wound Sparus aurata skin.
A1 Cerezo Ortega, Isabel M.
A1 Pérez-Gómez, Olivia
A1 Bautista-Moreno, Rocío
A1 Seoane, Pedro
A1 Esteban-Abad, María Ángeles
K1 Piel
AB Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish.Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administrationhas demonstrated beneficial effects for farmed fish, so its potential on the skin needs to be studiedmore deeply. The wounded specimens that received the diet with SpPdp11 showed a decrease inthe abundance of Enterobacteriaceae, Photobacterium and Achromobacter related to bacterial biofilmformation, as well as the overexpression of genes involved in signaling mechanisms (itpr3), cellmigration and differentiation (panxa, ttbk1a, smpd3, vamp5); and repression of genes related to cellproliferation (vstm4a, areg), consistent with a more efficient skin healing processes than that observedin the wounded control group. In addition, among the groups of damaged skin with different diets,Achromobacter, f_Ruminococcaceae, p_Bacteroidetes, Fluviicola and Flavobacterium genera with significantdifferences showed positive correlations with genes related to cell migration and negative correlationswith inflammation and cell proliferation and may be the target of future studies.
PB IOAP-MDPI
YR 2023
FD 2023-01-04
LK https://hdl.handle.net/10630/25998
UL https://hdl.handle.net/10630/25998
LA eng
NO Cerezo IM, Pérez-Gómez O, Bautista R, Seoane P, Esteban MÁ, Balebona MC, Moriñigo MA, Tapia-Paniagua ST. SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound Sparus aurata Skin. Animals. 2023; 13(2):193. https://doi.org/10.3390/ani13020193
NO Este estudio fue apoyado por subvenciones del Ministerio de Economía y Competitividad (MINECO) (AGL-2017-83370-C1-R y AGL-2017-83370-C3-R). Partial funding for open access charge: Universidad de Málaga
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026