RT Journal Article
T1 Analysis of foot function in terms of different pharmacological treatments in a cohort of patients with rheumatoid arthritis: a longitudinal study.
A1 Gámez-Guijarro, Maria
A1 Reinoso-Cobo, Andrés
A1 Pardo Rios, Manuel
A1 Ortega-Ávila, Ana Belén
A1 Ramos-Petersen, Laura
A1 Gijón-Noguerón, Gabriel
A1 Lópezosa-Reca, Eva
K1 Artritis reumatoide
K1 Pies
K1 Farmacología
AB This study examines the influence of pharmacological treatments on foot functionality in patients with rheumatoidarthritis over a five-year period. A longitudinal analysis categorized patients into different treatment groups,assessing their foot function using the Foot Function Index (FFI) at the start and end of the study. The groupsare based on their pharmacological treatment. Pharmacological treatment groups were categorized into: Imethotrexate (MTX), II MTX plus biological treatments (including all variables), III biological treatment alone, andIV a miscellaneous group comprising patients with diverse treatments, including patients for whom various drugshad failed or who had not achieved remission with pharmacological treatment. The study included 206 RA patientswith an average age of 58.32 years and a disease evolution of 15.28 years. The analysis of the FFI in total and acrossits domains of pain, disability, and activity revealed significant differences only in the pain domain (p=0.011), witha trend toward worsening over time observed in the other domains. Notably, MTX treatment showed improvementin the pain domain (decreasing from 45.76 in 2018 to 40.43 in 2023). Findings suggest that while pharmacologicaltreatments are essential in managing rheumatoid arthritis, their impact on foot function is limited, with MTXdemonstrating the most significant benefit in terms of pain reduction
PB BMC
YR 2025
FD 2025-04-16
LK https://hdl.handle.net/10630/38730
UL https://hdl.handle.net/10630/38730
LA eng
NO Gamez-Guijarro M, Reinoso-Cobo A, Pardo-Rios M, Ortega-Avila AB, Ramos-Petersen L, Gijon-Nogueron G, Lopezosa-Reca E. Analysis of foot function in terms of different pharmacological treatments in a cohort of patients with rheumatoid arthritis: a longitudinal study. BMC Rheumatol. 2025 Apr 16;9(1):43. doi: 10.1186/s41927-025-00495-x. PMID: 40241201; PMCID: PMC12001722.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026