RT Journal Article T1 Effectiveness of a muticomponent workout program integrated in an evidence based multimodal program in hyperfrail elderly patients: POWERAGING randomized clinical trial protocol A1 González-Sánchez, Manuel A1 Cuesta-Vargas, Antonio A1 Rodríguez González, María Del Mar A1 Díaz Caro, Elvira A1 Ortega Núñez, Germán A1 Galán-Mercant, Alejandro A1 Bedoya Belmonte, Juan José K1 Ejercicio físico K1 Ancianos - Cuidados AB Background: Short-term and mid-term comparison of the efficacy of a multimodal program that incorporates a therapeutic workout program, medication review, diet adjustment and health education, in comparison to the standard medical practice in the improvement of the neuromuscular and physiological condition. Methods: A randomized clinical trial of elderly frail patients drawn from the Clinical Management Unit "Tiro de Pichón", Health District of Malaga, will be included in the study (after meeting the inclusion / exclusion criteria) will be randomized in two groups: a control group that will undergo an intervention consistent of medication review + diet adjustment + health education (regular workout recommendations within a complete advice on healthy lifestyles) and an experimental group whose intervention will consist of a multimodal treatment: therapeutic workout program+ medication review+ diet adjustment + health education. The sociodemographic, clinical and tracing variables will be reflected at the beginning of the study. In addition, the follow-up variables will be gathered at the second and sixth months after the beginning of the treatment and at the third and sixth months after the treatment (follow-up). The follow-up variables that will be measured are: body mass index, general health condition, fatigue, frailty, motor control, attention- concentration- memory, motor memory, spatial orientation, grip strength, balance (static, semi-dynamic), gait speed and metabolomics. A descriptive analysis of the sociodemographic variables of the participants will be conducted.Discussion: A multimodal program that incorporates a therapeutic workout program, medication review, diet adjustment and health education may be effective treatment to reduce the functional decline in elderly. PB BMC Geriatr YR 2019 FD 2019-06-21 LK https://hdl.handle.net/10630/35762 UL https://hdl.handle.net/10630/35762 LA eng DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 22 ene 2026