RT Journal Article
T1 The transcriptional regulator JAZ8 interactswith the C2 protein from geminivirusesand limits the geminiviral infection in Arabidopsis
A1 Rosas-Díaz, Tábata Victoria
A1 Cana Quijada, José Francisco
A1 Wu, Mengshi
A1 Hui, Du
A1 Fernández‐Barbero, Gemma
A1 Macho, Alberto P.
A1 Solano, Roberto
A1 Castillo-Garriga, Araceli
A1 Wang, Xiao-Wei
A1 Lozano-Durán, Rosa
A1 Rodríguez-Bejarano, Eduardo
K1 Tomates - Enfermedades y plagas - Tratamiento
K1 Hormonas vegetales
AB Jasmonates (JAs) are phytohormones that finely regulate critical biological processes, including plant development and defense. JASMONATE ZIM-DOMAIN (JAZ) proteins are crucial transcriptional regulators that keep JA-responsive genes in a repressed state. In the presence of JA-Ile, JAZ repressors are ubiquitinated and targeted for degradation by the ubiquitin/proteasome system, allowing the activation of downstream transcription factors and, consequently, the induction of JA-responsive genes. A growing body of evidence has shown that JA signaling is crucial in defending against plant viruses and their insect vectors. Here, we describe the interaction of C2 proteins from two tomato-infecting geminiviruses from the genus Begomovirus, tomato yellow leaf curl virus (TYLCV) and tomato yellow curl Sardinia virus (TYLCSaV), with the transcriptional repressor JAZ8 from Arabidopsis thaliana and its closest orthologue in tomato, SlJAZ9. Both JAZ and C2 proteins colocalize in the nucleus, forming discrete nuclear speckles. Overexpression of JAZ8 did not lead to altered responses to TYLCV infection in Arabidopsis; however, knock-down of JAZ8 favors geminiviral infection. Low levels of JAZ8 likely affect the viral infection specifically, since JAZ8-silenced plants neither display obvious developmental phenotypes nor present differences in their interaction with the viral insect vector. In summary, our results show that the geminivirus-encoded C2 interacts with JAZ8 in the nucleus, and suggest that this plant protein exerts an anti-geminiviral effect.
PB Wiley
YR 2023
FD 2023
LK https://hdl.handle.net/10630/26515
UL https://hdl.handle.net/10630/26515
LA eng
NO Rosas-Diaz T, Cana-Quijada P, Wu M, Hui D, Fernandez-Barbero G, Macho AP, Solano R, Castillo AG, Wang XW, Lozano-Duran R, Bejarano ER. The transcriptional regulator JAZ8 interacts with the C2 protein from geminiviruses and limits the geminiviral infection in Arabidopsis. J Integr Plant Biol. 2023 Mar 22. doi: 10.1111/jipb.13482.
NO This work was supported by the Spanish Ministerio de Ciencia y Tecnología (PID2019-107657RB-C22) (ER-B), FEDER program (UMA20-FEDERJA-021) (AG-C), the Shanghai Center for Plant Stress Biology, the Chinese Academy of Sciences, and the Federal Ministry of Education and Research (BMBF) and the Baden-Württemberg Ministry of Science as part of the Excellence Strategy of the German Federal and State Governments (RL-D). TR-D was supported by a President's International Fellowship Initiative (PIFI) postdoctoral fellowship (No. 2016PB042) from the Chinese Academy of Sciences, the “Programa Juan de la Cierva” (IJCI-2017-33367) from the MCIN and FEDER program UMA20-FEDERJA-132 by AEI and by “ERDF A way of making Europe,” by the “European Union.” Funding for Open Access charge: Universidad de Málaga / CBUA.
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 19 ene 2026