RT Conference Proceedings T1 A bacterial acetyltransferase targets the protein kinase ZIP1, a positive regulator of plant immunity A1 Rufián Plaza, José Sebastián A1 Rueda-Blanco, Javier A1 López-Márquez, Diego A1 Beuzón-López, Carmen del Rosario A1 Ruiz-Albert, Francisco Javier K1 Bacterias patógenas AB Pseudomonas syringae is a model bacterial pathogen that penetrates the leaf to reach the plant apoplast, where it replicates causing disease. In order to do that, the pathogen must interfere and suppress a two-tiered plant defense response: PTI (PAMP-Triggered Immunity, or basal resistance) and ETI (Effector-Triggered Immunity). P. syringae uses a type III secretion system to directly deliver effector proteins inside the plant cell cytosol, many of which are known to suppress PTI, some of which are known to trigger ETI, and a handful of which are known to suppress ETI. Bacterial infection can also trigger a systemic plant defense response that protects the plant against additional pathogen attacks known as SAR (Systemic Acquired Resistance). We are particularly interested in the molecular and cellular mechanisms involved in effector-mediated defense evasion by P. syringae, in particular those involved in the suppression of ETI and SAR, and/or mediation of hormone signaling.Here we present data describing effector-mediated interference with plant immunity, by means of acetylation of a key positive regulator of local and systemic responses. Our work identifies a novel plant target for effector function, and characterizes its function. This work illustrates how analyzing the means by which a given effector interferes with its target can provide novel information regarding eukaryotic molecular mechanisms. YR 2016 FD 2016-06-27 LK http://hdl.handle.net/10630/11660 UL http://hdl.handle.net/10630/11660 LA spa NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. MINECO BIO2015-64391R y FEDER DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026