RT Conference Proceedings
T1 Differential Impacts of Acute, Chronic, and Social Defeat Stress on Microglial Morphology in the Amygdala and Habenula
A1 Zea-Doña, Alejandro
A1 Nieto-Quero, Andrea
A1 Infantes-López, M. Inmaculada
A1 Arjona, A.
A1 Tabbai-Amal, Sara
A1 Zambrana-Infantes, Emma
A1 Chaves-Peña, Patricia
A1 Muñoz-Martín, José
A1 Martín-Aguiar, Víctor
A1 Blanca-Mena, María José
A1 Pérez-Martín, Margarita
A1 Pedraza-Benítez, María del Carmen
K1 Microglia
K1 Núcleo amigdalino
K1 Neuropsiquiatría
K1 Estrés (Fisiología)
AB Stress is a major risk factor for neuropsychiatric disorders, including depression and post-traumatic stress disorder (PTSD), which disrupt emotional regulation and cognitive function. Microglia, the brain’sresident immune cells, play a critical role in maintaining neural homeostasis by modulating synaptic plasticity and responding to environmental challenges. Their morphological changes, such as alterations insoma size, density, and circularity, reflect distinct neuroimmune responses to stress. This study focuses on the basolateral (BLA) and central (CeA) amygdala, key for emotional processing, and the lateral (LHb)and medial (MHb) habenula, involved in motivation and reward. Understanding region-specific microglial adaptations to acute, chronic, and social defeat stress may help uncover mechanisms underlying stressvulnerability.
YR 2025
FD 2025
LK https://hdl.handle.net/10630/40203
UL https://hdl.handle.net/10630/40203
LA eng
DS RIUMA. Repositorio Institucional de la Universidad de Málaga
RD 20 ene 2026