RT Conference Proceedings T1 Association between chronic irritability and depressive symptoms in children and adolescents. A1 Busto Garrido, Marta A1 Gutiérrez-Castillo, D A1 Navas- Gonzalez, JR A1 Gutiérrez-Bedmar, Mario A1 Gutiérrez-Casares, JR A1 Martin-Lunar, MT A1 Rodríguez-Rosado-Martínez-Echevarría, Ana María A1 Pena-Andreu, José Miguel K1 Depresión en niños AB Chronic irritability is the most frequently reported symptom in child and adolescent depression. The association of both has been linked with high rates of chronicity, comorbility and impairment. ObjectivesTo study the association between chronic irritability and depressive symptoms in children and adolescents.MethodsWe have studied 857 participants recruited from the only Child and Adolescent Mental Health Clinic in a catchment area of 122968 people under 18 (2004-2010). A sample of 677 participants (57 controls and 620 patients) was included to carry out a cross-sectional study.Chronic irritability was measured by a Visual Analog Scale (VAS irritability) -scored from 0 to 10-, and depressive symptoms by the Children's Depression Inventory (CDI). The participants were categorized into controls and patients, and according to their chronic irritability (≤4 [I],5 [II] and ≥6 [III]). The mean of CDI score was calculated for each of the groups, adjusted by sex and age, and analyzed by ANCOVA.ResultsThe following means were obtained from the controls: 13,71 (group I), 9,82 (group II) and 17,45 (group III). Regarding to the patients: 13,92 (group I), 11,54 (group II) and 15,64 (group III). A quadratic association (p <0,0015) was found between VAS irritability score and CDI score.ConclussionsThere is not a lineal association between chronic irritability and depressive symptoms in children and adolescent. High rates of depressive symptoms were associated both with high and low rates of irritability. Several questions remain unexplained about the status of irritability in psychiatry as Stringaris group has been pointed out. Disclosure statement I have no potential conflict of interest to disclose YR 2017 FD 2017-09-21 LK http://hdl.handle.net/10630/14505 UL http://hdl.handle.net/10630/14505 LA eng NO Association between chronic irritability and depressive symptoms in children and adolescents. Busto-Garrido, M.; Gutierrez-Castillo, D; Navas- Gonzalez, JR; Gutierrez-Bedmar, M; Gutierrez-Casares, JR; Martin-Lunar, MT; Rodríguez-Rosado, A; Pena-Andreu, JM. European Psychiatry 415(2017) 5221. NO Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 25 ene 2026