RT Journal Article T1 Cross-cultural adaptation and psychometric validation of a Spanish version of the revised Patients’ Attitudes Towards Deprescribing (rPATD) questionnaire A1 De Juan-Roldán, José Ignacio A1 Castillo Jimena, Marcos A1 González Hevilla, Alba A1 Sánchez-Sánchez, Clara A1 García-Ruiz, Antonio J. A1 Gavilán Moral, Enrique K1 Psicometría K1 Medicamentos - Consumo - Aspectos psicológicos AB The present study was designed to validate a Spanish version of the rPATD questionnaire, both theversions for older adults and for caregivers, through a qualitative validation phase and the analysis of itspsychometric properties.Main outcome measures In the qualitative validation stage, the rPATD questionnaire was translated/back-translated and subjected to a cross-cultural adaptation to evaluate its face validity and feasibility. Next, its psychometric properties were assessed. Confirmatory factor analysis was used to evaluate construct validity. Internal consistency was determined using Cronbach’salpha test. Criterion validity through pre-established hypotheses from the Beliefs about Medicines Questionnaire (BMQ) Specific-Concerns Scale, and test– retest reliability were analysed.Results Confirmatory factor analysis verified the four-factor structure of the original rPATD questionnaire, with items loading into four factors: involvement, burden, appropriateness and concerns about stopping. The Cronbach’s alpha coefficient of the factors ranged from 0.683 to 0.879. The burden, appropriateness and concerns about stopping factors were significantly correlated with the BMQ Specific-Concerns Score, except for the concerns about stopping factor in the older adults’ version. The consistency of the items between administration times (test–retest reliability) showed weighted Cohen’s kappa values ranging from moderate(>0.4) to very good (>0.8).Conclusions The Spanish version of the rPATD questionnaire is a feasible, valid and reliable instrument to evaluate attitudes towards deprescribing in Spanish-speaking patients and caregivers. PB BMJ YR 2022 FD 2022-04-21 LK https://hdl.handle.net/10630/30301 UL https://hdl.handle.net/10630/30301 LA eng NO de Juan-Roldán JI, Castillo-Jimena M, González-Hevilla A, et al. Cross-cultural adaptation and psychometric validation of a Spanish version of the revised Patients’ Attitudes Towards Deprescribing (rPATD) questionnaire. BMJ Open 2022;12:e050678. NO CC BY DS RIUMA. Repositorio Institucional de la Universidad de Málaga RD 20 ene 2026